Semaphorins in stroke

 Your doctor should know of all of these and have a protocol to utilize them. No knowledge they need to be fired.  We have to clean out a lot of dead wood in stroke. You can see from the dates here that this has been around for a while. There is ABSOLUTELY NO EXCUSE  that our fucking failures of stroke associations haven't put together a protocol on this and distributed it to all stroke doctors and survivors.

Semaphorins and their Signaling Mechanisms January 2018

From there: 

Early studies revealed that semaphorins function as axon guidance molecules,(We need this to have our white matter do the connections needed.) but it is now understood that semaphorins are key regulators of morphology and motility in many different cell types including those that make up the nervous, cardiovascular, immune, endocrine, hepatic, renal, reproductive, respiratory and musculoskeletal systems, as well as in cancer cells.

 

Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D₂ Synthase September 2018

 

Following experimental stroke, the recovering brain is vulnerable to lipoxygenase‐dependent semaphorin signaling  October 2012

Serum semaphorin 7A is associated with the risk of acute atherothrombotic stroke  February 2019

Use of semaphorin-4D binding molecules to promote neurogenesis following stroke  May 2012

Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A  June 2011

Sustained up-regulation of semaphorin 3A, Neuropilin1, and doublecortin expression in ischemic mouse brain during long-term recovery  February 2008

 

Cellular and molecular mechanisms of neural repair after stroke: making waves April 2006