gingipains, periodontitis and alzheimer's

 Just maybe you want your doctor to be up-to-date on gingipains. Up to you if you want to enforce competency and get your gum disease treated while in the hospital.

Gingipains are trypsin-like cysteine proteinases produced by Porphyromonas gingivalis, a major causative bacterium of adult periodontitis.

Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors January 2019

Determining the presence of periodontopathic virulence factors in short-term postmortem Alzheimer's disease brain tissue April 2013

Porphyromonas gingivalis periodontal infection and its putative links with Alzheimer's disease April 2015

Alzheimer's disease-like neurodegeneration in Porphyromonas gingivalis infected neurons with persistent expression of active gingipains June 2020

Microglial Cathepsin B and Porphyromonas gingivalis Gingipains as Potential Therapeutic Targets for Sporadic Alzheimer's Disease September 2020

Porphyromonas gingivalis infection may contribute to systemic and intracerebral amyloid-beta: implications for Alzheimer's disease onset July 2020

Porphyromonas gingivalis and Alzheimer disease: Recent findings and potential therapies 

  June 2020

Interaction between genetic factors, Porphyromonas gingivalis and microglia to promote Alzheimer's disease September 2020

Linking mechanisms of periodontitis to Alzheimer's disease

April 2020