Thursday, May 27, 2021

Polytetrafluoroethylene coating fragments during neuroendovascular therapy: An analysis of two damaged microguidewires

 You'll need to be conscious enough after this procedure to ask your doctor what protocol they are following to ensure any fragments they leave behind in your brain cause no problems.

Polytetrafluoroethylene coating fragments during neuroendovascular therapy: An analysis of two damaged microguidewires

First Published May 26, 2021 Research Article 

Cerebral polymer coating embolism from intravascular devices represents a potentially serious complication to endovascular therapy (EVT). We report two cases of neuroendovascular treatment where filamentous polymer fragments were noted possibly due to damage of the surface coating during manipulation and backloading of microguidewires. As the exact origin of the debris was initially not known, microguidewires and fragments were examined with light microscopy, stereomicroscopy, scanning electron microscopy and attenuated-total-reflection Fourier transform infrared spectroscopy. Fragments consisted of polytetrafluoroethylene and silicone oil stemming from the proximal shaft of a standard microguidewire. To our knowledge, this is the first report of polytetrafluoroethylene coating fragments created during EVT. Future studies should assess the mechanism of polymer coating delamination and its potential consequences during EVT including inadvertent fragment migration into the cerebral circulation.

 

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