Abstract
Objective
To
investigate the potential benefits of three Therapeutic Instrumental
Music Performance (TIMP)-based interventions in rehabilitation of the
affected upper-extremity [UE] for adults with chronic post-stroke
hemiparesis.
Design
Randomized-controlled pilot study
Setting
University research facility
Participants
Thirty
community-dwelling volunteers [16 male/14 female; ages 33-76; mean age
=55.9] began and completed the protocol. All participants had sustained a
unilateral stroke > 6 months prior to enrollment [mean time
post-stroke =66.9 months].
Interventions
Two
baseline assessments, a minimum of one week apart; nine intervention
sessions (3x/wk for 3 wks), in which rhythmically-cued, functional arm
movements were mapped onto musical instruments; one post-test following
the final intervention. Participants were block-randomized to one of
three conditions: Group 1 - 45 minutes TIMP; Group 2 - 30 minutes TIMP,
15 minutes metronome-cued motor imagery (TIMP+cMI); Group 3 - 30 minutes
TIMP, 15 minutes motor imagery without cues (TIMP+MI). Assessors and
investigators were blinded to group assignment.
Main Outcome Measures
Fugl-Meyer Upper-Extremity (FM-UE); Wolf Motor Function Test- Functional Ability Scale (WMFT-FAS)
Secondary Measures
Motor Activity Log (MAL) – Amount of Use Scale; Trunk Impairment Scale.
Results
All groups made statistically significant gains on the FM-UE (TIMP, p=.005, r=.63; TIMP+cMI, p=.007, r=.63; TIMP+MI, p=.007, r=.61) and the WMFT-FAS (TIMP, p=.024, r=.53; TIMP+cMI, p=.008, r=.60; TIMP+MI, p=.008, r=.63). Comparing between-group percent change differences, on the FM-UE, TIMP scored significantly higher than TIMP+cMI (p=.032, r=.57),
but not TIMP+MI. There were no differences in improvement on WMFT-FAS
across conditions. On the MAL, gains were significant for TIMP (p=.030, r=.54) and TIMP+MI (p =.007, r=.63).
Conclusion
TIMP-based
techniques, with and without motor imagery, led to significant
improvements in paretic arm control on primary outcomes. Replacing a
physical training segment with imagery-based training resulted in
similar improvements; however, synchronizing internal and external cues
during auditory-cued motor imagery may pose additional sensorimotor
integration challenges.
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