Thursday, January 13, 2022

Clinical outcomes of rescue stenting for failed endovascular thrombectomy: a multicenter prospective registry

But you don't tell us the primary outcome; 100% recovery. As such you're not even trying to get stroke survivors recovered. WHAT THE HELL ARE YOU IN STROKE FOR?

Clinical outcomes of rescue stenting for failed endovascular thrombectomy: a multicenter prospective registry

  1. Jang-Hyun Baek1,2,
  2. Byung Moon Kim3,
  3. Eun Hyun Ihm4,
  4. Chang-Hyun Kim5,
  5. Dong Joon Kim3,
  6. Ji Hoe Heo2,
  7. Hyo Suk Nam2,
  8. Young Dae Kim2,
  9. Sangil Suh6,
  10. Byungjun Kim7,
  11. Yoodong Won8,
  12. Byung Hyun Baek9,
  13. Woong Yoon9,
  14. Hyon-Jo Kwon10,
  15. Yoonkyung Chang11,
  16. Cheolkyu Jung12,
  17. Hae Woong Jeong13
  1. Correspondence to Dr Byung Moon Kim, Radiology, Yonsei University College of Medicine, Seodaemun-gu, Seoul, Korea (the Republic of); bmoon21@hanmail.net

Abstract

Background Mechanical thrombectomy (MT) is a primary endovascular modality for acute intracranial large vessel occlusion. However, further treatment, such as rescue stenting, is occasionally necessary for refractory cases. We aimed to investigate the efficacy and safety of rescue stenting in first-line MT failure and to identify the clinical factors affecting its clinical outcome.

Methods A multicenter prospective registry was designed for this study. We enrolled consecutive patients who underwent rescue stenting for first-line MT failure. Endovascular details and outcomes, follow-up patency of the stented artery, and clinical outcomes were summarized and compared between the favorable and unfavorable outcome groups.

Results A total of 78 patients were included. Intracranial atherosclerotic stenosis was the most common etiology for rescue stenting (97.4%). Seventy-seven patients (98.7%) were successfully recanalized by rescue stenting. A favorable outcome was observed in 66.7% of patients. Symptomatic intracranial hemorrhage and mortality were observed in 5.1% and 4.0% of patients, respectively. The stented artery was patent in 82.1% of patients on follow-up angiography. In a multivariable analysis, a patent stent on follow-up angiography was an independent factor for a favorable outcome (OR 87.6; 95% CI 4.77 to 1608.9; p=0.003). Postprocedural intravenous maintenance of glycoprotein IIb/IIIa inhibitor was significantly associated with the follow-up patency of the stented artery (OR 5.72; 95% CI 1.45 to 22.6; p=0.013).

Conclusions In this multicenter prospective registry, rescue stenting for first-line MT failure was effective(What is your definition of effective? Mine is 100% recovery!) and safe. For a favorable outcome, follow-up patency of the stented artery was important, which was significantly associated with postprocedural maintenance of glycoprotein IIb/IIIa inhibitors.

Data availability statement

Data are available upon reasonable request. The relevant anonymized data are available on reasonable request.

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