Friday, April 22, 2022

Blood Pressure Management for Ischemic Stroke in the First 24 Hours

 

So we still have NO FUCKING CLUE what a blood pressure management protocol is. Hope you don't mind dying because of the cesspools of incompetence of the complete stroke medical world.  Unless YOU hold your stroke hospital's feet to the fire you are allowing your children and grandchildren to die or become disabled from their strokes.

5 years and still incompetent leadership in stroke.

Blood Pressure Management for Ischemic Stroke in the First 24 Hours

Originally publishedhttps://doi.org/10.1161/STROKEAHA.121.036143Stroke. 2022;53:1074–1084

High blood pressure (BP) is common after ischemic stroke and associated with a poor functional outcome and increased mortality. The conundrum then arises on whether to lower BP to improve outcome or whether this will worsen cerebral perfusion due to aberrant cerebral autoregulation. A number of large trials of BP lowering have failed to change outcome whether treatment was started prehospital in the community or hospital. Hence, nuances on how to manage high BP are likely, including whether different interventions are needed for different causes, the type and timing of the drug, how quickly BP is lowered, and the collateral effects of the drug, including on cerebral perfusion and platelets. Specific scenarios are also important, including when to lower BP before, during, and after intravenous thrombolysis and endovascular therapy/thrombectomy, when it may be necessary to raise BP, and when antihypertensive drugs taken before stroke should be restarted. This narrative review addresses these and other questions. Although further large trials are ongoing, it is increasingly likely that there is no simple answer. Different subgroups of patients may need to have their BP lowered (eg, before or after thrombolysis), left alone, or elevated.

Footnotes

Supplemental Material is available at https://www.ahajournals.org/doi/suppl/10.1161/STROKEAHA.121.036143.

For Sources of Funding and Disclosures, see page 1081.

Correspondence to: Philip Bath, DSc, FMedSci, Stroke Trials Unit, Queen’s Medical Centre, University of Nottingham, South Floor, D Floor, Nottingham NG7 2UH, United Kingdom. Email

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