Would this work for stroke and on humans? WHOM will be doing that research? With NO leadership in stroke, no followup ever occurs.
Well maybe there is something, ask your doctor about these results. Was not hard to find, Google scholar; 'vinpocetine stroke', that just shows you how fucking incompetent your stroke doctors and hospital are!
Vinpocetine for acute ischaemic stroke 2008
A systematic review of vinpocetine therapy in acute ischaemic stroke 1999
Anti-inflammatory effects of vinpocetine in atherosclerosis and ischemic stroke: a review of the literature 2014
Vinpocetine inhibits NF-κB-dependent inflammation in acute ischemic stroke patients 2018
Role of vinpocetine in ischemic stroke and poststroke outcomes: A critical review 2020 Vinpocetine increases cerebral blood flow and oxygenation in stroke patients: a near infrared spectroscopy and transcranial Doppler study 2002 This one is incredibly important immediately post stroke. What the fuck has your incompetent hospital done with it in 20 years?
The latest here:
Vinpocetine restores cognitive and motor functions in Traumatic brain injury challenged rats
Inflammopharmacology
(2022)
Abstract
Traumatic
brain damage is common worldwide and the treatments are not
well-defined. Vinpocetine is a synthetic derivative of the vinca
alkaloid vincamine and is clinically being used for various brain
disorders. Here in the current study, we have investigated the
neuroprotective potential of vinpocetine against traumatic brain injury.
TBI was induced by the Marmarou weight drop method in rats. Brain
damage was evaluated using cognitive and motor functions and the
alterations in biomolecules. Injured rats were treated with different
doses of vinpocetine (2.5, 5, and 10 mg/kg) for 4 weeks. Traumatic brain
injury in rats produced significant deterioration of cognition and
motor functions, which was accompanied by increased oxidative stress and
significant alterations in brain monoamine levels as compared with the
sham control group (p < 0.05). Vinpocetine alleviated
TBI-induced oxidative burden, altered neurochemistry, and improved the
cognitive and motor functions as compared with that of the TBI control
group (p < 0.05). The observed neuroprotective potential of
vinpocetine may be due to the observed antioxidant potential and its
ability to restore the levels of brain neurochemicals under stressed
conditions. The outcomes of the current study may help the repositioning
of vinpocetine for preventing or treating traumatic brain injuries.
This is a preview of subscription content, access via your institution.
Data availability
Enquiries about data availability should be directed to the authors
Inflammopharmacology (2022)
Abstract
Traumatic brain damage is common worldwide and the treatments are not well-defined. Vinpocetine is a synthetic derivative of the vinca alkaloid vincamine and is clinically being used for various brain disorders. Here in the current study, we have investigated the neuroprotective potential of vinpocetine against traumatic brain injury. TBI was induced by the Marmarou weight drop method in rats. Brain damage was evaluated using cognitive and motor functions and the alterations in biomolecules. Injured rats were treated with different doses of vinpocetine (2.5, 5, and 10 mg/kg) for 4 weeks. Traumatic brain injury in rats produced significant deterioration of cognition and motor functions, which was accompanied by increased oxidative stress and significant alterations in brain monoamine levels as compared with the sham control group (p < 0.05). Vinpocetine alleviated TBI-induced oxidative burden, altered neurochemistry, and improved the cognitive and motor functions as compared with that of the TBI control group (p < 0.05). The observed neuroprotective potential of vinpocetine may be due to the observed antioxidant potential and its ability to restore the levels of brain neurochemicals under stressed conditions. The outcomes of the current study may help the repositioning of vinpocetine for preventing or treating traumatic brain injuries.
This is a preview of subscription content, access via your institution.
Data availability
Enquiries about data availability should be directed to the authors
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