Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life

So with your increased risk of dementia post stroke your doctor will need to come up with OTHER EXACT PROTOCOLS TO PREVENT DEMENTIA.

 Your doctor's responsibility!

Your risk of dementia, has your doctor told you of this?

1. A documented 33% dementia chance post-stroke from an Australian study?   May 2012.

2. Then this study came out and seems to have a range from 17-66%. December 2013.`    

3. A 20% chance in this research.   July 2013.

4. Dementia Risk Doubled in Patients Following Stroke September 2018 

I'm going to be doing my own thing, which you shouldn't do since I'm not medically trained.

Dementia prevention 19 ways per Dean.

Risk reduction of cognitive decline and dementia: WHO guidelines

The latest here:

Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life

Flávia Borges-Machado, MSc https://orcid.org/0000-0002-8839-5726 f_93_machado@live.com.pt, Laetitia Teixeira, PhD, […], and Oscar Ribeiro, PhD+1View all authors and affiliations

OnlineFirst

https://doi.org/10.1177/08919887221149152

Abstract

Objective

To explore the effects of a multicomponent training (MT) physical exercise intervention in the cognitive function, neuropsychiatric symptoms, and quality of life of older adults with major neurocognitive disorder (NCD).

Methods

Quasi-experimental controlled trial. Thirty-six individuals (25 female) were equally distributed to an exercise group (aged 74.33 ± 5.87 years) or a control group (aged 81.83 ± 6.18 years). The Alzheimer’s Disease Assessment Scale – Cognitive (ADAS-Cog), the Neuropsychiatric Inventory (NPI) and the Quality of Life – Alzheimer’s Disease (QoL-AD) tests were performed before and after the intervention.

Results

There was no clear interaction effect factor of intervention on ADAS-Cog (B = 1.33, 95% CI: -2.61 – 5.28, P = .513), NPI (B = −8.35, 95% CI: −18.48 – 1.72, P = .115), and QoL-AD (B = 2.87, 95% CI: .01 – 5.73, P = .058).

Conclusions

The 6-month MT physical exercise intervention did not present evidence of slowing down cognitive decline neither improving neuropsychiatric symptomatology, and quality of life of older adults with major NCD. Future studies with larger samples are needed to better understand the impact of physical exercise interventions using MT methodology on specific cognitive abilities, neuropsychiatric symptoms, and quality of life domains.

Background

Along with the decline in cognitive function that characterizes a neurocognitive disorder (NCD), individuals may suffer from the progressive severity of behavioral and psychological symptoms (e.g., agitation, apathy, anxiety, hallucinations, eating disorders, nighttime behaviors) that often lead to a lower quality of life.¹

Physical exercise, as a promising non-pharmacological therapeutical approach within dementia care^2-4 is regularly recommended given its potential positive effects on cognitive function,^5-9 neuropsychiatric symptomatology,^10,11 and quality of life¹² of individuals with major NCD.

However, according to previous systematic reviews and meta-analytic studies, it remains unclear whether physical exercise might slow down the decline of global cognition or improve specific cognitive domains (i.e., executive functions, complex attention, memory, among other abilities).^13-16 Similarly, the role of physical exercise on alleviating challenging behaviours and mood disturbances is still limited^17-20 particularly in what regards other symptoms rather than depression.^16,21,22 Also, there’s still insufficient and inconsistent data on the effectiveness of well-promising physical exercise interventions on quality of life.^23-26

Multicomponent training (MT) (i.e., a combination of balance, strength, aerobic, gait and physical function training)²⁷ has been recently recommended for older adults with Alzheimer’s disease^2,28,29 and would seem advisable to individuals with major NCD due to other etiological conditions (e.g., vascular disease). Nevertheless, despite its positive influence on functional capacity,^30,31 few studies have focused on its effects on psychosocial outcomes. This study aims to explore the contribution of a 6-month community-based MT physical exercise intervention on the cognitive function, neuropsychiatric symptomatology, and quality of life of older adults diagnosed with major NCD.