Just talked to my doctor today about metformin, she said it's too early to tell, no clinical studies have been run on it yet. And since I'm not even pre-diabetic, I can't wheedle my way onto the drug.
You'll have to read about dietary restriction in this book: '
Ageless:The New Science of Getting Older Without getting Old'
Your doctor should have already gotten you protocols for IGF-1 with all the benefits already proven for stroke. So ask about those protocols.
IGF-1 (10 posts to March 2014)
Mechanisms of ageing: growth hormone, dietary restriction, and metformin
Published:February 24, 2023DOI:https://doi.org/10.1016/S2213-8587(23)00001-3
Summary
Tackling the mechanisms underlying ageing is desirable to help to extend the duration
and improve the quality of life. Life extension has been achieved in animal models
by suppressing the growth hormone–insulin-like growth factor 1 (IGF-1) axis and also
via dietary restriction. Metformin has become the focus of increased interest as a
possible anti-ageing drug. There is some overlap in the postulated mechanisms of how
these three approaches could produce anti-ageing effects, with convergence on common
downstream pathways. In this Review, we draw on evidence from both animal models and
human studies to assess the effects of suppression of the growth hormone–IGF-1 axis,
dietary restriction, and metformin on ageing.
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