Trichloroethylene: An Invisible Cause of Parkinson’s Disease?

 Well this might explain my Dad's Parkinsons. He was a car mechanic and owned his own gas station for about 10 years in his 20's.  I never got into cars so I should be good on this front.

Research suggested that trichloroethylene (TCE), an industrial solvent used in dry cleaning clothing and degreasing metal parts, was linked to Parkinson's disease

Trichloroethylene: An Invisible Cause of Parkinson’s Disease? 

Article type: Research Article

Authors: Dorsey, E. Ray^{a; b; 1; *} | Zafar, Maryam^{a; 1} | Lettenberger, Samantha E.^a | Pawlik, Meghan E.^a | Kinel, Dan^{a; b} | Frissen, Myrthe^c | Schneider, Ruth B.^{a; b} | Kieburtz, Karl^{a; b} | Tanner, Caroline M.^d | De Miranda, Briana R.^e | Goldman, Samuel M.^f | Bloem, Bastiaan R.^c

Affiliations: [a] Center for Health + Technology, University of Rochester Medical Center, Rochester, NY, USA | [b] Department of Neurology, University of Rochester Medical Center, Rochester, NY, USA | [c] Radboud University Medical Centre; Donders Institute for Brain, Cognition and Behaviour; Department of Neurology; Centre of Expertise for Parkinson & Movement Disorders; Nijmegen, the Netherlands | [d] Weill Institute for Neurosciences, Department of Neurology, University of California-San Francisco, San Francisco, CA, USA | [e] Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA | [f] Division of Occupational and Environmental Medicine, San Francisco Veterans Affairs Health Care System, School of Medicine, University of California–San Francisco, San Francisco, CA, USA

Correspondence: [*] Correspondence to: Ray Dorsey, MD, University of Rochester Medical Center, 265 Crittenden Blvd, CU 420694, Rochester, NY 14642, USA. Tel.: +1 585 275 0663; E-mail: ray.dorsey@chet.rochester.edu.

Note: [1] These authors contributed equally to this work.

Keywords: Air pollution, indoor air pollution, environment, Parkinson’s disease, solvents, tetrachloroethylene, trichloroethylene, water pollution, chemical water pollution

DOI: 10.3233/JPD-225047

Journal: Journal of Parkinson's Disease, vol. 13, no. 2, pp. 203-218, 2023

Accepted 31 January 2023

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Published: 14 March 2023