Tuesday, November 21, 2023

PSYCHEDELICS AND NEUROPLASTICITY: THE GOOD, THE BAD, AND THE PROMISING

Well, hasn't your doctor already prescribed various types of psychedelics to get you recovered? 

What about all these drugs for stroke recovery? Doesn't your doctor read the literature?

 

 PSYCHEDELICS AND NEUROPLASTICITY: THE GOOD, THE BAD, AND THE PROMISING

Stephen M. Stahl, MD, PhD, DSc (Hon.)
Clinical Professor, Department of Psychiatry and Neuroscience, University of California, Riverside
School of Medicine
Adjunct Professor, Department of Psychiatry, University of California, San Diego School of Medicine
Honorary Visiting Senior Fellow, University of Cambridge
Editor-in-Chief, CNS Spectrums
Director of Psychopharmacology Services, California Department of State Hospitals
Presented at the 2023 NEI Congress Psychedelics Workshop
Learning Objectives
•Explore the history of psychedelics and
psychiatry
•Describe the mechanism of action for
psychedelics, including how they promote
neuroplasticity, for the management of
psychiatric conditions
•Evaluate current evidence and opportunities for
future research and clinical applications
History of Psychedelics & Psychiatry
History of Psychedelics as Medicine
• Indigenous communities have utilized
psychedelics in traditional medicinal
rituals for thousands of years
• Current interest in psychedelics stems
from the synthesis and discovery of
lysergic acid diethylamide (LSD) by
Albert Hoffman in 1938 and
subsequent ingestion in 1943
• In the following years between 1950
and 1965, psychiatrists tested
psychedelics on a variety of
psychiatric disorders including alcohol
use disorder, schizophrenia, and
autism before…
LSD
Controlled Substances Act of 1970
• In 1970, the US government passed the Controlled Substances Act,
which established our current legal system where drugs are placed in
different schedules based on their perceived medical value and
addiction potential
• Despite the ongoing medical research on psychedelics at the time,
political movements resulted in psychedelics being placed in the
most restricted class of drugs: Schedule I
• The placement of psychedelics into Schedule I resulted in a halt of all
ongoing research into the medical value of psychedelics until the
recent so-called psychedelic renaissance

More at link.

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