Saturday, December 30, 2023

Alzheimer's disease could be slowed by common cholesterol-lowering medicine, study shows

But didn't your competent? doctor immediately prescribe statins to help in your recovery?

Or don't you have a functioning stroke doctor who incompetently missed this research from 2011?

1. Statins.

tested in rats from 2003

http://Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke  

Simvastatin Attenuates Stroke-induced Splenic Atrophy and Lung Susceptibility to Spontaneous Bacterial Infection in Mice

Or,

Simvastatin attenuates axonal injury after experimental traumatic brain injury and promotes neurite outgrowth of primary cortical neurons 

October 2012

tested in humans, March, 2011

http://www.medwirenews.com/39/91658/Stroke/Acute_statin_therapy_improves_survival_after_ischemic_stroke.html

And now lost even to the Wayback Machine

So I think this below is the actual research;

Association Between Acute Statin Therapy, Survival, and Improved Functional Outcome After Ischemic Stroke April 2011

The latest here:

Alzheimer's disease could be slowed by common cholesterol-lowering medicine, study shows

A new groundbreaking study showed that a common cholesterol-lowering blood pressure medication could slow cognitive decline in Alzheimer's patients.researchers, who conducted the study based on data from the Swedish Registry for Cognitive/Dementia Disorders and some other national data registries, studied the effects of statins, drugs that reduce cholesterol, including in the brain. Statins are defined by the U.S. Food & Drug Administration (FDA) as "a class of prescription drugs used together with diet and exercise to reduce blood levels of low-density lipoprotein (LDL) cholesterol ('bad cholesterol')."

READ MORE: But how does the drug reduce the cognitive decline of Alzheimer's and even some other forms of dementia?The answer lies in its ability to reduce congestion in blood pathways in the brain that can become filled with proteins, lipids like cholesterols or the beta amyloid amino acid that has recently been linked to Alzheimer's. When blood pathways get clogged, they can kill off brain cells. The National Institute on Aging states: "Abnormal levels of this naturally occurring protein clump together to form plaques that collect between neurons and disrupt cell function." And when cell function is disrupted, a person's cognitive ability can be drastically reduced. But one of the authors of the study, Sara Garcia-Ptacek, who is an associate professor of neuroscience at the Karolinska Institute in Stockholm, emphasized that the study isn't concrete and that more research needs to be done to determine the true correlation between the drugs and their ability to slow Alzheimer's disease. Garcia-Ptacek said another study is in order to confirm the results — the one that was published on Dec. 20 was observational, looking at past data and not deriving new data from an actual planned study that examines this particular link. The team looked at over 15,500 cases of people in Sweden who were diagnosed with dementia and who also had heart issues that required them to take statin or other blood pressure drugs. Of the group, about 4,500 did not use the drugs, while the other 11,000 or so did, and comparisons were drawn between both groups.Statin use was associated with a slower cognitive decline over time compared to no use of statins," the study concluded, but the authors added: "Some patients with AD [Alzheimer's disease] or mixed dementia with indication for lipid-lowering medication may benefit cognitively from statin treatment; however, further research is needed to clarify the findings of sensitivity analyses." Garcia-Ptacek added in a news release obtained by ScienceDaily: "The results of the study do not mean that we now have evidence that people with dementia should be treated with statins. But on the other hand, we can't see any support for not doing so. So, if a person needs statins for high blood lipids, a dementia diagnosis should not stop the treatment."

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