Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,372 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke. DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Wednesday, February 28, 2024
Outcomes and Predictors of Seizure Recurrence in Post-Stroke Epilepsy, A Retrospective Hospital-based Study
Predicting post stroke epilepsy rather than preventing it is the HEIGHT OF STUPIDITY! And you're still employed in stroke? Look how long we've known of the problem.
Recurrence in Post-Stroke seizure (PSS) is associated with significant functional decline in stroke patients.
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Choice of anti-seizure medications (ASMs) may influence the morbidity and mortality.
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Future research is needed to explore the effects of ASMs on PSS pathophysiology.
Abstract
Background
The
occurrence of seizures following a stroke is a well-recognized
complication associated with a significant increase in morbidity and
mortality. Despite the numerous studies examining outcomes and risk
factors related to post-stroke seizures (PSS), there remains a lack of
clarity(And you incompetently didn't create a protocol on how to prevent this problem?) regarding the clinical characteristics, treatment, and PSS
recurrence (PSSR) rates in patients experiencing their initial episode
of PSS.
Purpose
This
study aimed to determine the risk factors for developing recurrent
seizures after first PSS and their effects on functional outcomes and
mortality.
Methods
All
patients underwent an electroencephalography (EEG) and were monitored
for a minimum of 24 months following the first PSS. The primary endpoint
was the recurrence of seizures. Predictive factors for PSSR were
determined by using the Cox-proportional hazards model, and the
cumulative latency of recurrence at 90, 180, 360, and 720 days was
estimated using Kaplan-Meier analysis.
Results
Seizure
recurred in 36.8% (39/106). Significant association of PSSR was noted
with female gender, use of older anti-seizure medications (ASMs)
(p<0.001), EEG findings as focal slow wave activity (p<0.001),
Ictal epileptiform abnormalities (p=0.015), status epilepticus
(p=0.015), and with severe disability (p=0.008). However, multivariate
cox-proportional hazards model showed significant association of female
gender (HR=3.28; 95% CI: 1.42-7.58; p=0.006). Hazard ratio (HR) was
increased with older ASMs use, focal aware seizure types, Ictal EAs, and
periodic discharges on EEG; though, statistically significant.
Conclusion
Factors
such as the type of ASMs, EEG findings, and seizure type were
significantly linked to PSSR. Female gender was the only independent
predictor established. Additionally, significant functional decline was
reported with recurrence.
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