Implications for driving based on the risk of seizures after ischaemic stroke

Totally wrong research; SOLVE THE FUCKING PROBLEM! What is the EXACT PROTOCOL to prevent seizures?  Doesn't anyone in stroke have two functioning neurons to rub together for a spark of intelligence? You've known of seizures post stroke for years, why haven't you solved the problem?

Send me hate mail on this: oc1dean@gmail.com. I'll print your complete statement with your name and my response in my blog. Or are you afraid to engage with my stroke-addled mind?  Survivors would like to know why you are being so fucking incompetent!

 

• 10% seizures post stroke (19 posts to April 2017)

• 5% epileptic seizures after stroke (10 posts to April 2021)

• epileptic seizures (6 posts to December 2015)

• post-stroke epilepsy (7 posts to December 2016)

The latest crapola here:

 Implications for driving based on the risk of seizures after ischaemic stroke

1. http://orcid.org/0000-0003-1438-7544Kai Michael Schubert1,
2. Giulio Bicciato1,
3. Lucia Sinka1,2,
4. Laura Abraira3,
5. http://orcid.org/0000-0003-1915-0335Estevo Santamarina3,
6. José Álvarez-Sabín3,
7. Carolina Ferreira-Atuesta4,5,
8. Mira Katan1,6,
9. Natalie Scherrer1,
10. Robert Terziev1,
11. Nico Döhler7,8,
12. Barbara Erdélyi-Canavese7,
13. Ansgar Felbecker7,
14. Philip Siebel7,
15. Michael Winklehner9,
16. Tim J von Oertzen9,
17. http://orcid.org/0000-0002-0776-6821Judith N Wagner9,10,
18. Gian Luigi Gigli11,
19. Annacarmen Nilo11,
20. Francesco Janes11,
21. Giovanni Merlino11,
22. Mariarosaria Valente11,
23. María Paula Zafra-Sierra12,
24. Luis Carlos Mayor-Romero12,
25. Julian Conrad13,14,
26. S Evers13,15,
27. Piergiorgio Lochner16,
28. Frauke Roell16,
29. http://orcid.org/0000-0003-0928-1577Francesco Brigo17,
30. http://orcid.org/0000-0003-2399-7678Carla Bentes18,
31. Rita Peralta18,
32. Teresa Pinho e Melo18,
33. Mark R Keezer19,20,
34. http://orcid.org/0000-0002-1373-0681John Sidney Duncan4,
35. http://orcid.org/0000-0001-6041-9661Josemir W Sander4,19,21,
36. Barbara Tettenborn7,
37. Matthias Koepp4,
38. http://orcid.org/0000-0002-2307-071XMarian Galovic1,4

1. Correspondence to Dr Marian Galovic, Department of Neurology, Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, 8091, Switzerland; marian.galovic@usz.ch

Abstract

Background In addition to other stroke-related deficits, the risk of seizures may impact driving ability after stroke.

Methods 

 

We analysed data from a multicentre international cohort, including 4452 adults with acute ischaemic stroke and no prior seizures. We calculated the Chance of Occurrence of Seizure in the next Year (COSY) according to the SeLECT_2.0 prognostic model. We considered COSY<20% safe for private and <2% for professional driving, aligning with commonly used cut-offs.

Results 

Seizure risks in the next year were mainly influenced by the baseline risk-stratified according to the SeLECT_2.0 score and, to a lesser extent, by the poststroke seizure-free interval (SFI). Those without acute symptomatic seizures (SeLECT_2.0 0–6 points) had low COSY (0.7%–11%) immediately after stroke, not requiring an SFI. In stroke survivors with acute symptomatic seizures (SeLECT_2.0 3–13 points), COSY after a 3-month SFI ranged from 2% to 92%, showing substantial interindividual variability. Stroke survivors with acute symptomatic status epilepticus (SeLECT_2.0 7–13 points) had the highest risk (14%–92%).

Conclusions 

Personalised prognostic models, such as SeLECT_2.0, may offer better guidance for poststroke driving decisions than generic SFIs. Our findings provide practical tools, including a smartphone-based or web-based application, to assess seizure risks and determine appropriate SFIs for safe driving.

Data availability statement

Data are available on reasonable request. Who can access the data: Data will be shared on a reasonable request by a qualified investigator, provided consent to share is given by the individual cohorts. Types of analyses: For any purpose on reasonable request by a qualified investigator. Mechanisms of data availability: With investigator support.

http://creativecommons.org/licenses/by-nc/4.0/

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