Sunday, July 21, 2024

Alzheimer's breakthrough as nasal spray may boost memory

 In mice, so don't expect anything in your children's or grandchildren's lifetime

Alzheimer's breakthrough as nasal spray may boost memory

Nasal sprays could revolutionize Alzheimer's treatment by swiftly delivering brain-boosting medicine and improving cognitive function, a new study shows.

This research is the latest in recent years to show showing promising results that support nasal therapy as a potential treatment for degenerative brain conditions.

Researchers at the Mitchell Center for Neurodegenerative Diseases, University of Texas, tested a spray containing tiny lipophilic micelles (oil/fat particles that can carry substances through water) on aging mice, administering the treatment through their noses.

These findings could guide the development of more effective treatments for Alzheimer's and related diseases.

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The bulk of recent studies indicating the same outcomes could bring hope to the 6.9 million Americans who are living with Alzheimer's at present.

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With the global number of sufferers projected to exceed 78 million by 2030, breakthroughs like this are crucial.

Model Brain Held By Scientist
A model of a human brain being held in a hand. To get an antibody into the brain rapidly, a team put it into tiny packages called micelles and delivered it through mice's nose. Photo by Matthew Horwood/Getty Images


Nasal sprays are a promising new treatment for Alzheimer's because they deliver medicine directly to the brain quickly and effectively.

The intranasal solution was found to improve their cognitive function. This was achieved through the development of a confirmation-specific antibody (TTCM2)—a type which recognizes and binds to a protein only when that protein is in a specific shape or form.

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