Abstract
Objective
To
identify the predictors of minimal clinically important changes in
actual and perceived functional arm use of the affected upper limb after
rehabilitative therapy.
Design
Retrospective, observational cohort study.
Setting
Outpatient rehabilitation settings.
Participants
A cohort of 94 patients with chronic stroke.
Interventions
Patients received robot-assisted therapy, mirror therapy, or combined therapy for 4 weeks.
Main Outcome Measures
The
primary outcome measures, assessed pre- and post intervention, included
actual functional arm use measured by an accelerometer and perceived
functional arm use measured by the Motor Activity Log (MAL). Candidate
predictors included age, sex, time after stroke, side of stroke, and
scores on the Fugl-Meyer Assessment, Modified Ashworth Scale, Medical
Research Council scale, Wolf Motor Function Test, MAL (quality of
movement), and Nottingham Extended Activities of Daily Living.
Results
Being
male (odds ratio [OR], 3.17; 95% CI, 1.13-8.87) and having a higher
than median Medical Research Council score (OR, 2.68; 95% CI, 1.12-6.41)
significantly predicted minimal clinically important changes assessed
by an accelerometer. Fugl-Meyer Assessment scores (odds ratio, 1.06; 95%
CI, 1.02-1.11) were a significant predictor of achieving clinically
important changes in MAL amount of use. Wolf Motor Function Test
(quality) scores (OR, 3.05; 95% CI, 1.38-6.77) could predict clinically
important improvements in MAL quality of movement.
Conclusions
Predictors
of clinically important changes in the use of the affected upper limb
after robot-assisted therapy, mirror therapy, or combined therapy in
patients with chronic stroke for 4 weeks differ for actual vs perceived
use. Further studies are recommended to validate these findings in a
larger sample.
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