Isn't your competent? doctor already using non-invasive vagus nerve stimulation for your recovery? Oh, but you don't have a functioning stroke doctor, do you?
Non-invasive VNS approach could enhance post-stroke recovery outcomes August 2023
vagus nerve (67 posts to July 2012)
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The latest here:
Mechanically Compliant and Impedance Matching Hydrogel Bioelectronics for Low‐Voltage Peripheral Neuromodulation
PDFAbstract
In neural biointerfacing technologies, mitigating the mismatch in mechanical and impedance attributes between neural tissues and bioelectronics remains a central challenge for achieving high-efficacy neuromodulation. Here, full-hydrogel bioelectronics that demonstrate superior mechanical compliance and impedance matching with 3D peripheral nerves, allowing for low-voltage vagus nerve stimulation, are reported. By precisely tuning the dimensional parameters through 3D printing, the hydrogel bioelectronics, initially in a 2D planar form in a dehydrated state, can curl spontaneously around nerves and form a seamless interface. During the hydration process, instant, and tough bioadhesion is achieved through a dry crosslinking mechanism, enabling a mechanically robust nerve-electrode interface to resist dynamic yet vigorous deformations of the peripheral nerve systems. The as-formed nerve-electrode interface significantly mitigates the impedance mismatch, in favor of electrical stimulation at a threshold voltage of 10 mV, one order of magnitude lower than that of conventional metallic electrodes. The use of the hydrogel bioelectronics for successful stroke rehabilitation through low-voltage vagus nerve stimulation in a rat model is also demonstrated.
Graphical Abstract
Hydrogel bioelectronics for low-voltage peripheral neuromodulation: Selfcurling hydrogel bioelectronics establish a multifunctional platform for lowvoltage peripheral neuromodulation, enabling tailored designs to accommodate diverse nerve curvatures through precise geometric optimization. These devices seamlessly integrate with neural tissues and are validated in a rat stroke model, demonstrating precise neuromodulation achieved via low-current stimulation.
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