Long-Term Follow-Up of Participants in the Taking Charge After Stroke Randomized Controlled Trial

 

Motivation for survivors is easy: 100% recovery protocols! AND YOU WERE TOO FUCKING DUMB TO FIGURE THAT OUT?  It takes a stroke survivor to educate you blithering idiots!

My conclusion is you don't understand ONE GODDAMN THING ABOUT SURVIVOR MOTIVATION/DEMORALIZATION, DO YOU? You create EXACT 100% recovery protocols, and your survivor will be motivated to do the millions of reps needed because they are looking forward to 100% recovery. I'd fire all of you for absurd incompetence! GET THERE!

Long-Term Follow-Up of Participants in the Taking Charge After Stroke Randomized Controlled Trial

Alexander Martin, BSc (Hons) https://orcid.org/0000-0002-0131-5480, Vivian Fu, PhD https://orcid.org/0000-0002-0989-3672, Zamir Joya, DipPharm https://orcid.org/0009-0000-0450-0369, Sajida Joya https://orcid.org/0009-0003-2488-6395, Allie Eathorne, MAppStat, Mark Weatherall, FRACP https://orcid.org/0000-0002-0051-9107, Gabrielle Shortt, PhD, Alex Semprini, PhD https://orcid.org/0000-0003-0949-0555, John Gommans, FRACP https://orcid.org/0000-0003-3750-765X, and Harry McNaughton, PhD https://orcid.org/0000-0003-3030-6062 harry.mcnaughton@mrinz.ac.nzAuthor Info & Affiliations

Stroke

New online

https://doi.org/10.1161/STROKEAHA.125.052545

Abstract

BACKGROUND:The take charge intervention—a conversation-based, community intervention to improve motivation, improved independence, and physical health 12 months after stroke in 2 randomized controlled trials with 572 participants. This article reports long-term outcomes for the 400 participants in the TaCAS study (Taking Charge After Stroke).Follow-up study of a New Zealand multicenter, randomized, controlled, parallel-group trial. Outcomes were collected by postal questionnaire or telephone call. The TaCAS study recruited 400 participants discharged after stroke, randomized within 16 weeks to one of 3 groups: 1 session of the take charge intervention, 2 sessions 6 weeks apart, or no sessions (control). This study is of participants still alive and willing to answer a questionnaire 5 to 6 years after their index stroke, undertaken in 2022. The primary outcome was the Physical Component Summary of the Short Form 36, comparing the take charge intervention and control. Secondary outcomes were: Frenchay Activities Index; modified Rankin Scale (mRS); survival; and stroke recurrence. These outcomes were compared with those 12 months after stroke. Analysis was by ANOVA or logistic regression.

RESULTS:Mortality data were available for all 400 participants, and functional data for 204/297 (69%) of survivors. The mean difference (95% CI) in Physical Component Summary between take charge and control groups was 2.8 (−0.8 to 6.5) units, P=0.12, and for independence (modified Rankin Scale score, 0–2) the odds ratio (95% CI) was 0.56 (0.28–1.16), P=0.11, both favoring take charge with similar point estimates to those after 12 months. Differences between take charge and control participants for Frenchay Activities Index scores, survival, and stroke recurrence were small and nonsignificant.

CONCLUSIONS:The clinically significant improvements in physical health and independence for take charge participants, observed at 12 months, were sustained 5 to 6 years after stroke, but no longer statistically significant.

REGISTRATION:URL https://anzctr.org.au; Unique identifier: ACTRN12622000311752.

Graphical Abstract

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