I'm not sure what research was behind this so ask your doctor. Your doctor knows everything. I'm not sure I like patenting stroke methods.
http://eon.businesswire.com/news/eon/20121217006462/en/Patent/Neuronal-Disorders/Stroke
The European Patent Office notified Genervon of its intention to grant a
European patent on Methods of Treating Neuronal Disorders using MNTF
peptides and analogs thereof. Genervon will proceed to have the patents
for EPO application No. 07867451.2 issued, bringing the portfolio of
Genervon’s issued Composition of Matters and Use patents to 46.
This patent will grant the intellectual property rights to the use of
GM600 in the preparation of a medicament for the therapeutic treatment
of neuronal diseases and disorders including stroke, cerebral ischemia,
spinal cord injuries (SCI), Huntington’s disease (HD), Parkinson’s
disease (PD), multiple sclerosis (MS), amyotrophic lateral sclerosis
(ALS), and Alzheimer’s disease by intravenous delivery.
Genervon has discovered a novel endogenous embryonic stage family of 9
human master regulators of the nervous system. The company has developed
one of the master regulators, named GM600, for disease modification in
neurodegenerative diseases and for neuroprotection. A Phase 1 clinical
trial in human volunteers by bolus intravenous administration was
completed and GM600 is very safe and tolerable at very high multiple
doses. A GM600 serial number is assigned to each indication. GM602 and
GM608 are assigned to ischemic stroke and Parkinson’s disease,
respectively, which are in Phase 2 clinical trials. GM604 is assigned to
ALS indication, with promising and comprehensive mechanisms of action.
GM600 provided neuroprotection against soluble inflammatory factors from
CNS human patients’ cerebral spinal fluid (CSF) in vitro by the
following percent increase of neuronal cells: Stroke (205%), ALS (175%),
MS (246%), AD (191%), HD (271%), PD (198%). GM600 has shown very
efficacious effects in animal models in many neurodegenerative and acute
injury models.
The discovery of endogenous embryonic stage human master regulators is
changing the drug development paradigm from hitting a single
gene/pathway to a comprehensive and dynamic multi-factorial approach to
treat complex neurodegenerative diseases. Genervon is at the forefront
of a drug development paradigm shift that is beginning to be appreciated.
Genervon Biopharmaceuticals LLC (www.genervon.com) is
an innovative clinical stage biopharmaceutical company providing
breakthrough biological drugs for some of the world’s critical unmet
medical needs.
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