What are the long-term effects of using nicotine gum?

Ask your doctor if they have finally concluded that nicotine is helpful in stroke recovery.  But don't listen to me, I'm obviously delusional to even consider challenging the medical gods.
1.  Nicotine Holds Promise for Stronger Stroke Recovery
2.  Nicotine Patch Appears To Help Mild Cognitive Loss
3.  A Nicotine Patch a Day Keeps the Cognitive Impairment Away
4. Chronic nicotine restores normal Aβ levels and prevents short-term memory and E-LTP impairment in Aβ rat model of Alzheimer's disease
5. Nicotinic receptors in aging and dementia


and the negative;
1. Nicotine's role in promoting heart and blood vessel disease
 


http://well.blogs.nytimes.com/2013/01/24/ask-well-long-term-use-of-nicotine-gum/
In small doses, like those contained in the gum, nicotine is generally considered safe. But it does have stimulant properties that can raise blood pressure, increase heart rate and constrict blood vessels. One large report from 2010 found that compared to people given a placebo, those who used nicotine replacement therapies had a higher risk of heart palpitations and chest pains.