This is all in preparation for a night session held by Sparrow hospital.
Latest Advancements in Acute Stroke Management April 17, 2013
I
want to ask appropriate questions without having them dismiss my
questions just because I know more than they do on the subject. Medical
persons are touchy that way. You aren't important because you haven't
the training to understand this complexity. My questions are going to
be on what they are specifically doing to stop apoptosis or necrosis of brain cells.
You didn't mention any hypothermia in either the ambulance or the ER. Is hypothermia not yet considered ready for prime time?
The only ischemic treatment you specified in the first week is tPA. Are there no treatments in the first week that research has identified as neuroprotective or that can stop the neuronal cascade of death?
Maybe ibuprofen?, Viagra?, amantadine?, minocycline?, levodopa?, statins?, fish oil?, anti-depressants?, Paeoniflorin?, Inhalation of nitric oxide?, Melatonin?, Glibenclamide?, Etazolate?,
linagliptin?, edaravone used in Japan since 2001, Enzogenol from New Zealand, Draculin?,PSD-95 inhibitors tested in monkeys.
For neuroprotection, which path do you consider the most promising?
1. Excitotoxicity
2. Glutamate poisoning
3. Capillaries that don't open due to pericytes
4. Inflammatory action leaking through the blood brain barrier
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