Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, March 12, 2013

What I am going to insist I get after my next stroke

This is totally not to be followed. Your doctors advice needs to be followed even though they are doing nothing to stop the neuronal cascade of death. Assisting by inaction in the death of your neurons. None of these have any human clinical trial proof so  don't expect an easy time getting your doctor to listen to you.  I want the kitchen sink thrown at saving my neurons.

Your doctor better have something similar planned and you need to demand the protocol now.  Winging it is not appropriate medical practice.

Better yet, Ask your doctor what they would do in the first week to save neurons for their stroke, if they don't have anything to say, get rid of them as a doctor.

I'm going to have to get a medic alert bracelet with this URL engraved.

0. Ambulance ride - hypothermia applied

  Have them stop at that frozen lake and dunk you in it.

Study of Brain Cooling and Clot-Busting Drug Therapy for Stroke Receives FDA OK to Expand 

February 2013

0.1  blood pressure cuffs in the ambulance ride

http://oc1dean.Can Blood-Pressure Cuffs Work? Novel Ways to Limit Stroke Damage 

December 2012

1. Statins.

tested in rats from 2003

http://Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke  

Simvastatin Attenuates Stroke-induced Splenic Atrophy and Lung Susceptibility to Spontaneous Bacterial Infection in Mice

Or,

Simvastatin attenuates axonal injury after experimental traumatic brain injury and promotes neurite outgrowth of primary cortical neurons 

October 2012

tested in humans, March, 2011

http://www.medwirenews.com/39/91658/Stroke/Acute_statin_therapy_improves_survival_after_ischemic_stroke.html

And now lost even to the Wayback Machine

So I think this below is the actual research;

Association Between Acute Statin Therapy, Survival, and Improved Functional Outcome After Ischemic Stroke April 2011

 

2. Fish oil.

     either by injection

Fish oil ‘may help stroke patients’

March 2013

     or a feeding tube

Fish oil for brain injuries - TBI 

October 2012

3.  Leg compressions

Leg compressions may enhance stroke recovery 

August 2012

4. anti-depressants -  real ones

Scottish News Stroke study into antidepressants

December 2012

5. music listening

music listening and stroke rehab 

March 2011

6. Sensation overload

   the human equivalent of rat whisker stimulation.

Mild Sensory Stimulation Completely Protects the Adult Rodent Cortex from Ischemic Stroke 

May 2012

7. Coffee - I want many cups a day, where is 24 hour a day coffee station?

Coffee may help perk up your blood vessels

    reduce my dementia chances

delay my Alzheimers chances

reduce my Parkinsons risk

8. CerAxon

Introducing CerAxon®, the First & Only Oral Solution Medical Food for Dietary Management of Brain Ischemia in Patients With Partially Impaired Swallow

October 2011

Bobs' use of it from Pink House on the Corner.

CerAxon: The Verdict is In

9.  Peptide application

Tarix Pharmaceuticals' Peptide Technology Stimulates Revascularization Following Ischemia 

March 2013

10. Action observation

 Videos of everything from walking, running, jumping to finger ballet, baseball throwing, piano playing, eating. Every minute of the day not spent in traditional rehab should be watching videos, including during meals, that would work on multitasking.

a.  Clinical Relevance of Action Observation in Upper-Limb Stroke Rehabilitation 

May 2012

b.  Action observation and mirror neuron network: a tool for motor stroke rehabilitation

April 2012

c.  The Impressionable Brain and mirror neurons

May 2011

d.  Action observation of walking/running 

May 2012

11.  bFGF administered intravenously

Potential Usefulness of Basic Fibroblast Growth Factor as a Treatment for Stroke

March 2013

12. Viagra - Ladies, I don't know how you're going to convince your doctor why you need this, maybe say its for your spouse and you want to make sure your lady parts are still working. Only tested in rats.

viagra and stroke rehab 

March 2011

13.  Training in lucid dreaming.

Scientists Measure Dream Content for the First Time: Dreams Activate the Brain in a Similar Way to Real Actions 

July 2012

14.  Eptifibatide

Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke (CLEAR-ER)

February 2013

15.  dietary olive leaf extract

Effect of dietary olive leaf extract on brain cholesterol, cholesterol ester and triglyceride levels and of brain edema in rat stroke model

January 2013

16. ebselen - neuroprotective treatment? within 48 hours

ebselen - neuroprotective treatment? 

December 2012

17.  diabetes drug linagliptin

Diabetes drug may reduce brain damage after stroke

December 2012

18. Etazolate, an α-secretase activator

Etazolate, an α-secretase activator, reduces neuroinflammation and offers persistent neuroprotection following traumatic brain injury in mice 

November 2012

19.  Glibenclamide - administered intravenously 6, 12, and 24 hours after reperfusion

Glibenclamide enhances neurogenesis and improves long-term functional recovery after transient focal cerebral ischemia 

November 2012

20.   Paeoniflorin (PF) - PF treatment for 14 days

Paeoniflorin Protects against Ischemia-Induced Brain Damages in Rats via Inhibiting MAPKs/NF-κB-Mediated Inflammatory Responses 

November 2012

21.  administration of nontoxic carbon particles 

Halting Brain Injury

October 2012

22.  Ibuprofen

Common Medicine Helps Repair Brain After Stroke, Study in Rats Suggests 

October 2012

23.  Ceria nanoparticles

Ceria nanoparticles could lessen the damage from ischemic strokes

September 2012

24.  Head-of-Bed Optimization of Elevation

HOBOE (Head-of-Bed Optimization of Elevation) Study: association of higher angle with reduced cerebral blood flow velocity in acute ischemic stroke

May 2012

25.   antibiotic minocycline

Antibiotic may be new stroke treatment 

May 2012

26.   neurotransmitter precursor levodopa

Early Promise For Stroke Patients Given - levodopa

May 2012

27.   Inhalation of nitric oxide

Inhalation of nitric oxide could help improve blood flow to ischemic brain 

March 2012

28.  old flu drug amantadine

Study: Old flu drug speeds brain injury recovery 

February 2012

29.  Melatonin 

Melatonin ameliorates neural function by promoting endogenous neurogenesis through MT2 melatonin receptor in ischemic stroke mice

February 2012

and

Melatonin improves neuroplasticity by upregulating the growth-associated protein 43 (GAP-43) and NMDAR-post-synaptic density-95 (PSD95) proteins in cultured neurons exposed to glutamate excitotoxicity and in rats subjected to transient focal cerebral ischemia even during a long-term recovery period 

December 2013

30.   opiate antagonists — Effects of exogenous antagonists and dynorphin 1–13  - damn this war on drugs

Treatment of stroke with opiate antagonists — Effects of exogenous antagonists and dynorphin 1–13 

January 2012

I don't give a damn if this is considered practicing medicine, anything else is criminally negligent.

I challenge anyone at the Joint Commission/WSO to come up with something better. Anyone willing to take up that challenge? I will post an unedited reply.
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2 comments:

  1. AmyMarch 13, 2013 at 2:51 AM

    Dean I'm going to Peter's seminar today.......

    ReplyDelete
  2. Billy EthridgeMarch 13, 2013 at 9:19 PM

    I relish this post, Dean! You are a scrappy, honest, bitterly witty, occasionally all-out funny, intelligent as with a moving knife, stroke-wise yet humble, and helpful to all stroke survivors or anyone interested in their well being. Recommendtion: perhaps sadly, often gleefully and regularly read his posts (all the more if you're a neurologist). Weep and counterintuitively enjoy! ~from a survivor of a massive hemorrhagic stroke...

    ReplyDelete

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