Image Challenge from New England Journal of Medicine

Does your doctor use this to diagnose you?
http://www.nejm.org/image-challenge

The answer to the image challenge this week is #1 - Atherosclerosis.  Most of you got the right answer because you obviously know that the diagonal crease seen in the earlobe is known as "Frank's sign".  The sign was originally described as a marker for coronary artery disease, with a moderate sensitivity ( approximately 48%) and specificity ( approximately 88%).  Frank's sign has been associated with other cardiovascular risk factors like atherosclerosis.
Thanks to Toni Brayer of

EverythingHealth for pointing this out.

I must have atherosclerosis since my right carotid artery is totally blocked but I have no crease in my ears.