Tuesday, November 12, 2013

PET Imaging Technique Finds Plaques 'Ripe for Rupture'

This is probably what I should have had done after my dad was diagnosed with 85% blockage in his left carotid artery. But that would have required his doctor being trained well enough to know that blockage might be hereditary.

PET Imaging Technique Finds Plaques 'Ripe for Rupture'


Positron-emission tomography (PET) can identify recently ruptured atherosclerotic plaques or those at risk of rupture in patients using the metabolic tracer 18F-sodium fluoride (18F-NaF), suggests a small prospective observational study[1].
Focal uptake of the tracer in the coronaries "informs about calcification activity, which is believed to be a healing response to intense plaque inflammation," according to the study's lead author, Dr Nikhil V Joshi (University of Edinburgh, Scotland). It was seen in the culprit artery of >90% of the group's patients with recent acute MI and in more than a third of those with stable coronary disease, he explained to heartwire .
Plaques with concentrations of increased tracer uptake showed features linked to rupture risk (positive remodeling, microcalcification, large necrotic core) at coronary computed tomography (CT) and intravascular ultrasound (IVUS), those findings supported by carotid endarterectomy tissue histology.

More at link and names for your doctor to talk to if needed.

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