Wednesday, June 4, 2014

Effect of high potassium diet on endothelial function

You'll have to ask your doctor to get the complete article to find out what the hell the difference between high and low is. I try and do 3 bananas a day for the stroke risk reduction. Potassium 21%   Why eat three bananas a day?
You'll have to ask your doctor to translate this gobbledygook into layperson terms. Exactly how much of what foods should you be eating. Damn it, you're paying them, have them work for their pay.  Having smooth linings of your arteries is a good thing, I think.

http://www.mdlinx.com/internal-medicine/newsl-article.cfm/5306724/ZZF307965849E94474BB34FC062CEC0F93/?

Nutrition, Metabolism & Cardiovascular Diseases,  Clinical Article

Blanch N, et al. – The aim was to determine the effect of increased dietary potassium from fruit and vegetables on endothelial function. The finding suggest that increased dietary potassium from fruit and vegetables improves flow mediated dilatation (FMD) within 1 week in healthy men and women but the mechanisms for this effect remain unclear.
Methods
  • Thirty five healthy men and women (age 32 ± 12 y) successfully completed a randomised cross–over study of 2 × 6 day diets either high or low in potassium.
  • Flow mediated dilatation (FMD), BP, pulse wave velocity (PWV), augmentation index (AI) and a fasting blood sample for analysis of Intercellular Adhesion Molecule–1 (ICAM–1), E–selectin, asymmetric dimethylarginine (ADMA) and endothelin–1 were taken on completion of each intervention.
Results
  • Dietary change was achieved by including bananas and potatoes in the high potassium and apples and rice/pasta in the low potassium diet.
  • Dietary adherence was assessed using 6 day weighed food diaries and a 24 h urine sample.
  • The difference in potassium excretion between the two diets was 48 ± 32 mmol/d (P = 0.000).
  • Fasting FMD was significantly improved by 0.6% ± 1.5% following the high compared to the low potassium diet (P = 0.03).
  • There were no significant differences in BP, PWV, AI, ICAM–1, ADMA or endothelin–1 between the interventions.
  • There was a significant reduction in E–selectin following the high (Median = 5.96 ng/ml) vs the low potassium diet (Median = 6.24 ng/ml), z = -2.49, P = 0.013.
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