No clue, you'll have to ask your doctor to translate to layperson terms.
http://search.naric.com/research/rehab/redesign_record.cfm?search=2&type=all&criteria=J68099&phrase=no&rec=124277
NARIC Accession Number: J68099. What's this?
ISSN: 0031-9023.
Author(s): Cassidy, Jessica M.; Gillick, Bernadette T.; Carey, James R..
Publication Year: 2014.
Number of Pages: 12.
Abstract: Article relates the concept of
metaplasticity, as derived from studies in humans who are healthy, to
stroke rehabilitation and consider how it can be leveraged to maximize
stroke outcomes. Repetitive transcranial magnetic stimulation (rTMS) is
emerging as a potentially valuable intervention to augment the effects
of behavioral therapy for stroke. When used in conjunction with other
therapies, rTMS embraces the concept of metaplasticity. Due to
homeostatic mechanisms inherent to metaplasticity, interventions known
to be in isolation to enhance excitability can interact when applied
successively under certain timing conditions and produce enhanced or
opposite effects. Similar to “muscular wisdom,” with its self-protective
mechanisms, there also appears to be “synaptic wisdom” in neural
networks with homeostatic processes that prevent over- and
under-excitability. These processes have implications for both enhancing
and suppressing the excitability effects from behavioral therapy.
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