Tuesday, September 23, 2014

Managing ICH - A statin onboard may be a life-saver for intracerebral hemorrhage patients

You can have your doctors argue this out. As long as they get a stroke protocol written up prior to you  showing up at the hospital with another stroke. YOU are going to have to get on your stroke department head and force the issue to be solved because if you don't intervene I bet nothing will be done because this is somebody else's problem.
Good luck with getting your stroke medical world to take some f*cking responsibility for saving neurons.
http://www.medpagetoday.com/Cardiology/Strokes/47785?
Spontaneous intracerebral hemorrhage (ICH) patients did better on a statin during hospitalization, an observational study showed.
The likelihood of survival was 4.25-fold greater for ICH patients on a statin than among nonusers at 30 days after the hemorrhage (P<0.001), Alexander C. Flint, MD, PhD, of Kaiser Permanente Northern California in Redwood City, and colleagues found.
Inpatient statin users were also 2.57-times more likely to be discharged home or to an acute rehabilitation facility (P<0.001), the researchers reported online in JAMA Neurology.
However, statin users taken off the drug when entering the hospital for ICH showed a higher risk of both outcomes than statin users (OR 0.16 for 30-day survival and OR 0.26 for discharge home or to acute rehab, P<0.001 for both).
"The particular association between cessation of statin use and worsened outcomes merits careful consideration of the risk-benefit balance of discontinuing statin therapy in the acute setting of ICH," the researchers concluded.
However, there's more to consider than this single study, Marco A. Gonzalez-Castellon, MD, and Randolph S. Marshall, MD, both of Columbia University Medical Center in New York City, noted in an accompanying editorial.
"The controversy regarding statin use and ICH is far from settled," they wrote, although they agreed that "For now, however, it provides sufficient evidence to recommend at least the continuation of statin therapy after nonamyloid ICH for at least 30 days after the initial event."
Studies have come down on either side of the issue, and either direction of association is feasible mechanistically, they explained.

More at link.

No comments:

Post a Comment