This is just a press release so I have no idea if the clinical study actually supports these conclusions.
Self reporting like this is somewhat suspect as to veracity.
http://www.internationalstemcell.com/profiles/investor/NewsPrint.asp?b=1468&ID=76350&m=rl&pop=1&Nav=1&g=583&t=1363
Human
parthenogenetic neural stem cells (ISC-hpNSC) can significantly reduce
neurological dysfunction after a stroke in animal models, according to
recent experiments conducted by International Stem Cell Corporation (OTCQB: ISCO), a California-based biotechnology company developing novel stem cell based therapies and biomedical products.
"With
no approved treatments for neurological dysfunction, individuals who
have suffered a stroke have few treatment options available beyond
physical rehabilitation following recovery," stated Ruslan Semechkin
Ph.D., the company's chief scientific officer. "These new results are
highly encouraging, suggesting that ISC-hpNSC may have significant
ability to not only reduce but also reverse these neurological symptoms
of dysfunction. These findings not only broaden the future potential use
of our neural stem cells beyond Parkinson's disease but also offer hope
to a patient population with a significant unmet medical need."
Neural
stem cells work to repair the brain in several ways. The cells are
attracted to the site of injury(proven where?) and in response to signals released by
the damaged tissue release a range of molecules that reduce inflammation
and trigger the recovery process. Neural stem cells have the ability to
make the various neurological cell types to replace the dead and dying
cells necessary for the formation of new brain tissue. In this way the
hpNSCs act as coordinators of all the various activities necessary to
recover brain function.
ISCO's
stroke program uses the same neural stem cells as the company's
Parkinson's disease program, derived from the Company's human
parthenogenetic stem cells using a cGMP method based on the protocol
published in Nature Scientific Reports in March 2013 (click here).
Parthenogenetic neural stem cells have been shown in peer-reviewed
publications to have superior immunological properties to other neural
stem cells. The complete dataset will be presented at an upcoming
scientific conference to be announced separately. Further studies
investigating the potential for treating stroke are planned.
According
to the National Stroke Association stroke is a leading cause of death
in the United States, killing nearly 130,000 people each year, and is a
leading cause of serious, long-term adult disability. Approximately
795,000 strokes will occur each year, one occurring every 40 seconds,
and taking a life approximately every four minutes. Approximately two
million brain cells die every minute during stroke, increasing the risk
of permanent brain damage, disability or death. The estimated direct and
indirect cost of stroke in the United States in 2010 is $73.7 billion.
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