A Randomized Trial of Cardiovascular Responses to Energy Drink Consumption in Healthy Adults

But did they consider those studies that have identified a single nugget of our DNA that seems to determine whether we process caffeine quickly or slowly?

 A Randomized Trial of Cardiovascular Responses to Energy Drink Consumption in Healthy Adults

Anna Svatikova, MD, PhD¹; Naima Covassin, PhD¹; Kiran R. Somers¹; Krishen V. Somers, BS, BA¹; Filip Soucek, MD¹; Tomas Kara, MD, PhD¹; Jan Bukartyk, MSc¹

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JAMA. 2015;314(19):2079-2082. doi:10.1001/jama.2015.13744.

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This randomized clinical trial of young healthy volunteers assessed the association between energy drink consumption and cardiovascular responses.

Energy drink consumption has been associated with serious cardiovascular events,^1- 4 possibly related to caffeine and other stimulants. We hypothesized that drinking a commercially available energy drink compared with a placebo drink increases blood pressure and heart rate in healthy adults at rest and in response to mental and physical stress (primary outcomes). Furthermore, we hypothesized that these hemodynamic changes are associated with sympathetic activation, which could predispose to increased cardiovascular risk (secondary outcomes).