Comprehensive cellular-resolution atlas of the adult human brain

Which one of these atlases is your doctor using to show you the damage to your brain and explain the disabilities that come from that? Do you get a cool 3d rendering of it?

The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture

New brain atlas opens up alternative means for studying brain disorders

Stereoscopic Atlas of Intrinsic Brain Networks (SAIBN)

 

 

The latest here:

Comprehensive cellular-resolution atlas of the adult human brain

1. Song-Lin Ding^1,*,
2. Joshua J. Royall¹,
3. Susan M. Sunkin¹,
4. Lydia Ng¹,
5. Benjamin A. C. Facer¹,
6. Phil Lesnar¹,
7. Angie Guillozet-Bongaarts¹,
8. Bergen McMurray¹,
9. Aaron Szafer¹,
10. Tim A. Dolbeare¹,
11. Allison Stevens²,
12. Lee Tirrell²,
13. Thomas Benner²,
14. Shiella Caldejon¹,
15. Rachel A. Dalley¹,
16. Nick Dee¹,
17. Christopher Lau¹,
18. Julie Nyhus¹,
19. Melissa Reding¹,
20. Zackery L. Riley¹,
21. David Sandman¹,
22. Elaine Shen¹,
23. Andre van der Kouwe²,
24. Ani Varjabedian²,
25. Michelle Write²,
26. Lilla Zollei²,
27. Chinh Dang¹,
28. James A. Knowles³,
29. Christof Koch¹,
30. John W. Phillips¹,
31. Nenad Sestan⁴,
32. Paul Wohnoutka¹,
33. H. Ronald Zielke⁵,
34. John G. Hohmann¹,
35. Allan R. Jones¹,
36. Amy Bernard¹,
37. Michael J. Hawrylycz¹,
38. Patrick R. Hof⁶,
39. Bruce Fischl² and
40. Ed S. Lein^1,*

DOI: 10.1002/cne.24080

© 2016 Wiley Periodicals, Inc.

Issue

Journal of Comparative Neurology

Accepted Article (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Additional Information(Show All)

Author InformationPublication History

SEARCH

Search Scope

Search String

• Advanced >
• Saved Searches >

ARTICLE TOOLS

• Get PDF (56892K)
• Save to My Profile
• E-mail Link to this Article
• Export Citation for this Article
• Get Citation Alerts

Share|

• Abstract
• Cited By

Get PDF (56892K)

Keywords:

• brain atlas;
• cerebral cortex;
• hippocampal formation;
• thalamus;
• hypothalamus;
• amygdala;
• cerebellum;
• brainstem;
• MRI;
• DWI;
• cytoarchitecture;
• parvalbumin;
• neurofilament protein;
• RRIDs: AB_10000343;
• AB_2314904;
• SCR_014329

ABSTRACT

Detailed anatomical understanding of the human brain is essential for unraveling its functional architecture, yet current reference atlases have major limitations in terms of lack of whole-brain coverage, relatively low image resolution, and sparse structural annotation. We present the first digital human brain atlas to incorporate neuroimaging, high-resolution histology, and chemoarchitecture across a complete adult female brain, consisting of MRI, DWI, and 1356 large-format cellular resolution (1 µm/pixel) Nissl and immunohistochemistry anatomical plates. The atlas is comprehensively annotated for 862 structures, including 117 white matter tracts and several novel cyto- and chemoarchitecturally defined structures, and these annotations were transferred onto the matching MRI dataset. Neocortical delineations were done for sulci, gyri, and modified Brodmann areas to link macroscopic anatomical and microscopic cytoarchitectural parcellations. Correlated neuroimaging and histological structural delineation allowed fine feature identification in MRI data and subsequent structural identification in MRI data from other brains. This interactive online digital atlas is integrated with existing Allen Institute for Brain Science gene expression atlases and is publicly accessible as a resource for the neuroscience community. This article is protected by copyright. All rights reserved.

Get PDF (56892K)