Effect of Exhaust- and Nonexhaust-Related Components of Particulate Matter on Long-Term Survival After Stroke

It is obvious that after your stroke you can no longer live in a polluted city unless your doctor gives you other interventions that neutralize that risk.
Like maybe a 307%  stroke risk reduction from these 11 possibilities?  
Effect of Exhaust- and Nonexhaust-Related Components of Particulate Matter on Long-Term Survival After Stroke

Anita Desikan, Siobhan Crichton, Uy Hoang, Benjamin Barratt, Sean D. Beevers, Frank J. Kelly and Charles D.A. Wolfe

http://dx.doi.org/10.1161/STROKEAHA.116.014242

Stroke. 2016;47:2916-2922

Originally published November 3, 2016

Abstract

Background and Purpose—Outdoor air pollution represents a potentially modifiable risk factor for stroke. We examined the link between ambient pollution and mortality up to 5 years poststroke, especially for pollutants associated with vehicle exhaust.

Methods—Data from the South London Stroke Register, a population-based register covering an urban, multiethnic population, were used. Hazard ratios (HR) for a 1 interquartile range increase in particulate matter <2.5 µm diameter (PM_2.5) and PM <10 µm (PM₁₀) were estimated poststroke using Cox regression, overall and broken down into exhaust and nonexhaust components. Analysis was stratified for ischemic and hemorrhagic strokes and was further broken down by Oxford Community Stroke Project classification.

Results—The hazard of death associated with PM_2.5 up to 5 years after stroke was significantly elevated (P=0.006) for all strokes (HR=1.28; 95% confidence interval [CI], 1.08–1.53) and ischemic strokes (HR, 1.32; 95% CI, 1.08–1.62). Within ischemic subtypes, PM_2.5 pollution increased mortality risk for total anterior circulation infarcts by 2-fold (HR, 2.01; 95% CI, 1.17–3.48; P=0.012) and by 78% for lacunar infarcts (HR, 1.78; 95% CI, 1.18–2.66; P=0.006). PM₁₀ pollution was associated with 45% increased mortality risk for lacunar infarct strokes (HR, 1.45; 95% CI, 1.06–2.00; P=0.022). Separating PM_2.5 and PM₁₀ into exhaust and nonexhaust components did not show increased mortality.

Conclusions—Exposure to certain outdoor PM pollution, particularly PM_2.5, increased mortality risk poststroke up to 5 years after the initial stroke.