Saturday, December 24, 2016

Effect of Wheel Running on Neurogenesis in Subventricular Zone of Adult Rats post Cerebral Ischemia

What is the human equivalent of rat wheel running?  Why doesn't your doctor know that answer? Incompetence? Stupidity? Doesn't care? Waiting for somebody else to address that issue? Has your doctor read any of the research references so you can recover better?
http://pesquisa.bvsalud.org/enfermeria/resource/es/wpro-933390
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Jie FANG; Xi-quan HU.
Artículo en Ch | WPRIM | ID: wpro-933390

Resumen

Objective To observe the effect of wheel running exercise on subventricular zone neurogenesis and the neural function in rats post cerebral ischemia. Methods 48 adult male Sprague-Dawley rats were induced cortical infarcts with left middle artery occlusion and were housed in either standard (control group, n=24) or wheel running (exercise group, n=24). They were assessed with neurological severi-ty scores (NSS), and the expression of Ki67 was determined with immunofluorescence, 3, 7, 14 and 21 days after training. Results Com-pared with the control group, the number of Ki67-labeled cells in subventricular significantly increased in the exercise group 14 and 21 days after ischemia (P<0.05), and the NSS decreased since 7 days after ischemia (P<0.05). Conclusion Wheel running may promote the neuro-genesis in subventricular of adult rats after cerebral infarction, which may associate with the recovery of neural function.
Biblioteca responsable: WPRO

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