Introduction
Acute
stroke unit care, intravenous thrombolysis and endovascular treatment
significantly improve the outcome for patients with ischaemic
stroke, but data on access and delivery throughout Europe
are lacking. We assessed best available data on access and
delivery of acute stroke unit care, intravenous thrombolysis and
endovascular treatment throughout Europe.
Methods
A
survey, drafted by stroke professionals (ESO, ESMINT, EAN) and a
patient organisation (SAFE), was sent to national stroke
societies and experts in 51 European countries (World Health
Organization definition) requesting experts to provide national data on
stroke unit, intravenous thrombolysis and endovascular
treatment rates. We compared both pooled and individual
national data per one million inhabitants and per 1000 annual
incident ischaemic strokes with highest country rates. Population
estimates were based on United Nations data, stroke
incidences on the Global Burden of Disease Report.
Results
We
obtained data from 44 European countries. The estimated mean number of
stroke units was 2.9 per million inhabitants (95% CI
2.3–3.6) and 1.5 per 1000 annual incident strokes (95% CI
1.1–1.9), highest country rates were 9.2 and 5.8. Intravenous
thrombolysis was provided in 42/44 countries. The estimated mean
annual number of intravenous thrombolysis was 142.0 per
million inhabitants (95% CI 107.4–176.7) and 72.7 per 1000
annual incident strokes (95% CI 54.2–91.2), highest country rates were
412.2 and 205.5. Endovascular treatment was provided in
40/44 countries. The estimated mean annual number of
endovascular treatments was 37.1 per million inhabitants (95% CI
26.7–47.5) and 19.3 per 1000 annual incident strokes (95% CI
13.5–25.1), highest country rates were 111.5 and 55.9.
Overall, 7.3% of incident ischaemic stroke patients received
intravenous thrombolysis (95% CI 5.4–9.1) and 1.9% received
endovascular treatment (95% CI 1.3–2.5), highest country
rates were 20.6% and 5.6%.
Conclusion
We
observed major inequalities in acute stroke treatment between and
within 44 European countries. Our data will assist decision
makers implementing tailored stroke care programmes for
reducing stroke-related morbidity and mortality in Europe.
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