Relative intake of macronutrients impacts risk of mild cognitive impairment or dementia

Is this enough for your doctors and stroke hospital to come up with SPECIFIC diet protocols? Or will they wait for SOMEONE ELSE TO SOLVE THE PROBLEM?

If they wait it likely will be at least 50 years before it is done, incompetence at its finest.

 

Relative intake of macronutrients impacts risk of mild cognitive impairment or dementia

Roberts RO¹, Roberts LA, Geda YE, Cha RH, Pankratz VS, O'Connor HM, Knopman DS, Petersen RC.

Author information

1

Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. roberts.rosebud@mayo.edu

Abstract

High caloric intake has been associated with an increased risk of cognitive impairment. Total caloric intake is determined by the calories derived from macronutrients. The objective of the study was to investigate the association between percent of daily energy (calories) from macronutrients and incident mild cognitive impairment (MCI) or dementia. Participants were a population-based prospective cohort of elderly persons who were followed over a median 3.7 years (interquartile range, 2.5-3.9) of follow-up. At baseline and every 15 months, participants (median age, 79.5 years) were evaluated using the Clinical Dementia Rating scale, a neurological evaluation, and neuropsychological testing for a diagnosis of MCI, normal cognition, or dementia. Participants also completed a 128-item food-frequency questionnaire at baseline; total daily caloric and macronutrient intakes were calculated using an established database. The percent of total daily energy from protein (% protein), carbohydrate (% carbohydrate), and total fat (% fat) was computed. Among 937 subjects who were cognitively normal at baseline, 200 developed incident MCI or dementia. The risk of MCI or dementia (hazard ratio, [95% confidence interval]) was elevated in subjects with high % carbohydrate (upper quartile: 1.89 [1.17-3.06]; p for trend = 0.004), but was reduced in subjects with high % fat (upper quartile: 0.56 [0.34-0.91]; p for trend = 0.03), and high % protein (upper quartile 0.79 [0.52-1.20]; p for trend = 0.03) in the fully adjusted models. A dietary pattern with relatively high caloric intake from carbohydrates and low caloric intake from fat and proteins may increase the risk of MCI or dementia in elderly persons.

PMID:

22810099

PMCID:

PMC3494735

DOI:

10.3233/JAD-2012-120862

[Indexed for MEDLINE]

Free PMC Article