Association of midlife diet with subsequent risk for dementia

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Association of midlife diet with subsequent risk for dementia

JAMA — Akbaraly TN, et al. | March 14, 2019

In this prospective cohort study involving 8,225 participants without dementia, researchers ascertained if midlife (mean age: 50 years) diet is correlated with subsequent dementia risk. According to findings, the quality of the diet evaluated during midlife was not significantly related to subsequent dementia risk.

Methods

• This was a population-based cohort study established in 1985-1988 in which researchers assessed dietary intake in 1991-1993, 1997-1999, and 2002-2004, and followed-up for incident dementia until March 31, 2017.
• Diet quality during midlife was assessed using the Alternate Healthy Eating Index (AHEI; diet quality score (score range, 0-110), with higher scores indicating a healthier diet.
• The main outcome assessed was incident dementia, which was determined by electronic health records linkage.