Bad research since it doesn't take into account the protective effects of coffee on Parkinsons and dementia. Not complete enough research.
How coffee protects against Parkinson’s Aug. 2014
Coffee May Lower Your Risk of Dementia Feb. 2013
Long-term coffee consumption, caffeine metabolism genetics, and risk of cardiovascular disease: A prospective analysis of up to 347,077 individuals and 8,368 cases
American Journal of Clinical Nutrition — Zhou A, et al. | March 12, 2019
Researchers used data from the UK
Biobank, as well as logistic regression, to examine whether the link
between habitual coffee consumption and cardiovascular disease (CVD)
risk varied with CYP1A2 (a functional variant at cytochrome
P450 1A2) genotype or a genetic score for caffeine metabolism
(caffeine-GS). They analyzed data for 347,077 individuals, with 8,368
incident CVD cases. An elevated CVD risk was reported for nondrinkers,
drinkers of decaffeinated coffee, and those who reported drinking >6
cups/day vs those drinking 1–2 cups/day (increase in odds by 11%, 7%,
and 22%, respectively). A modest increase in CVD risk was observed in
association with heavy coffee consumption, but genetic variants
affecting caffeine metabolism had no impact on this link.
Read the full article on American Journal of Clinical Nutrition
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