Flavonoid intake and MRI markers of brain health in the Framingham Offspring cohort

Notice that this doesn't apply to us and our fucking failures of stroke associations

won't do the necessary studies to see how this might help stroke survivors. Don't do anything with this unless your doctor prescribes it. And since quartiles are not explained here your doctor needs to get the full clinical research so you know exactly how many bottles of red wine you should be consuming. My doctor told me I had a bunch of white matter hyperintensities but never showed me them on any scan, so I don't know the size or any intervention needed, because my doctor knew nothing.

The main dietary sources of flavonoids include tea, citrus fruit, citrus fruit juices, berries, red wine, apples, and legumes. Individual flavonoid intakes may vary considerably depending on whether tea, red wine, soy products, or fruit and vegetables are commonly consumed.

Flavonoid intake and MRI markers of brain health in the Framingham Offspring cohort

The Journal of Nutrition — Shishtar E, et al. | March 26, 2020

Researchers assessed MRI measures of brain health, including total brain tissue volume, white matter hyperintensities volume (WMHV), and hippocampal volume, in correlation with the intake of dietary flavonoid. Participants included members of the Framingham Heart Study Offspring Cohort who were free of stroke at exam 7 and had at least 1 valid food frequency questionnaire from exams 5, 6, or 7 (n = 2,086; mean age at exam 7, 60.6 y). Flavonoid intakes were grouped according to quartiles categories of consumption. In the highest quartile category of flavan-3-ols and flavonoid polymers intake vs in the lowest quartile category, the mean (95% CI) of the WMHV of participants was found to be significantly smaller after accounting for crucial demographic, lifestyle, and clinical factors. For flavan-3-ols and flavonoid polymers as well as for total flavonoids, inverse trend links with WMHV were also noted. The findings revealed a likely impact of higher flavonoid intakes on the risk of Alzheimer disease and related dementias (ADRD) in middle-aged and older adults, by causing a decrease in WMHV, a marker strongly related to ADRD. These findings contribute to the literature on flavonoids and ADRD.

Read the full article on The Journal of Nutrition