Thursday, September 16, 2021

Cerebral blood volume index as a predictor of functional independence after basilar artery thrombectomy

Why would you think any survivor wants to hear about your prediction of failure to recover? They want EXACT STROKE PROTOCOLS TO 100% RECOVERY! GET THERE!  Or find another job.

Cerebral blood volume index as a predictor of functional independence after basilar artery thrombectomy

 
First published: 14 September 2021

Funding information:

None.

Abstract

Background and Purpose

The role of CT perfusion (CTP)in the evaluation of acute basilar artery occlusion (aBAO) patients undergoing endovascular thrombectomy (EVT) is unclear. We investigated the association of individual CTP parameters with functional outcomes in aBAO patients undergoing EVT.

Methods

A health system's prospectively collected code stroke registry was used in this retrospective analysis of aBAO patients treated with EVT presenting between January 2017 and February 2021 with pre-EVT CTP. The primary outcome measure was modified Rankin Scale (mRS) score 0-2 at 90 days. Factors with a univariate association (p < .05) with mRS 0-2 were combined in a multivariable regression model to determine independent predictors of 90-day favorable functional outcome.

Results

Forty-six subjects, with median age 67 years and median National Institutes of Health Stroke Scale 16, were included, of whom 17 (37%) achieved mRS 0-2 at 90 days. In the multivariable logistic regression model, CTP cerebral blood volume (CBV) index (per 0.1-point increase, odds ratio = 1.843; 95% confidence interval: 1.039, 3.268; p-value .0365) was independently associated with a favorable 90-day outcome.

Conclusions

CBV index was independently associated with a favorable 90-day outcome in aBAO patients treated with EVT, a novel finding in this patient population. CBV index may assist in treatment and prognosis discussions and inform future studies investigating the role of CTP in aBAO.(What are you doing to get to 100% recovery when this index is low?)

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