Establishing the underlying biomechanics of acute ischemic stroke
(AIS) and its treatment is fundamental to developing more effective
clinical treatments for one of society’s most impactful diseases. Recent
changes in AIS management, driven by clinical evidence of improved
treatments, has already led to a rapid rate of innovation(Really? Where is that innovation located?), which is
likely to be sustained for many years to come. These unprecedented AIS
triage and treatment innovations provide a great opportunity to better
understand the disease. In this article we provide a perspective on the
recreation of AIS in the laboratory to inform contemporary device design
and procedural techniques in mechanical thrombectomy.
Presentation of these findings, which have been used to solve the
applied problem of designing mechanical thrombectomy devices, is
intended to help inform the development of basic biomechanics solutions
for AIS.
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