Sunday, April 2, 2023

Evolution of Brain Activation with Good and Poor Motor Recovery after Stroke

In the following 17 years, HAS YOUR INCOMPETENT DOCTORS AND HOSPITAL DONE ONE DAMN THING WITH THIS TO GET SURVIVORS RECOVERED?

Not that I see anything useful here but your doctor should have created some useful research from this.

Evolution of Brain Activation with Good and Poor Motor Recovery after Stroke

 March 2006, Neurorehabilitation and Neural Repair


Abstract

Objective
 
To characterize the evolution of brain activation in stroke patients with variable motor recovery and quantify changes relative to healthy controls.  
 
Methods
 
Serial PET activation studies, using a simple finger-tapping task, and quantitative measures of motor performance were obtained in 9 patients (2-7 weeks poststroke and 6 months later) and compared with serial healthy volunteer data. 
 
Results. 
Patients with moderate impairment and good recovery (n = 5) activated the primary sensorimotor cortex (SM1) contralateral to the paretic hand moved, bilateral supplementary motor area (SMA), contralateral cingulate gyrus, and ipsilateral lateral premotor cortex. Activation in the bilateral SMA was greater at the initial study but reduced over time compared to healthy controls and poor recoverers. Patients with severe impairment and poor recovery (n =4) showed limited activation of contralateral SM1 and SMA at both studies and no significant change over time. A posterior shift in SM1 activation was evident in good and poor recoverers.  
 
Conclusions. 
 
Activation of typical motor regions and recruitment of additional sites occur subacutely poststroke, with evolution to normal patterns in moderately impaired patients who recover well. In comparison, severely impaired, poor-recovery patients show persistent, reduced activation. Dynamic changes in SMA, differentially observed in good recoverers over 6 months, highlight its importance in recovery.
 
 

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