So you'll want your competent? doctor to not have any of these triggers go off if you have a PFO!
Meaning:
Vaccines for flu, pneumonia, RSV, COVID-19.
No high intensity exercise of any sort.
Trigger Factors In Patients With A Patent Foramen Ovale Associated Stroke: A Case-Crossover Study
Abstract
Background:
Patent
foramen ovale (PFO) is a congenital anatomical variant which is
associated with strokes in young adults. Contrary to vascular risk
factors and atherosclerosis, a PFO is present from birth. However, it is
completely unknown how an anatomical structure that is already present
at birth in a large proportion of the population, can convert into a PFO
that causes stroke in a few. Recent studies reported a significant
association between certain trigger factors and ischemic stroke in young
adults. This study aims to investigate these triggers in PFO-associated
stroke.
Methods:
The
ODYSSEY Study, a multicenter prospective cohort study between 2013 and
2021, included patients aged 18-49 years experiencing their first-ever
ischemic event. Participants completed a questionnaire about exposure to
potential trigger factors. A case-crossover design was used to assess
the relative risks (RR) with 95% confidence intervals (95% CI). The
primary outcome was the relative risk of potential trigger factors for
PFO-associated stroke.
Results:
1043
patients completed the questionnaire and had an ischemic stroke of
which 124 patients had a PFO-associated stroke (median age 42.1 years,
45.2% men). For patients with PFO-associated stroke the RR was 26.0 (95%
CI 8.0-128.2) for fever, 24.2 (95% CI 8.5-68.7) for flu-like disease
and RR 3.31 (95% CI 2.2-5.1) for vigorous exercise.
Conclusion:
In
conclusion, flu-like disease, fever and vigorous exercise may convert
an asymptomatic PFO into a stroke causing PFO in young adults.
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