Contour Neurovascular System for endovascular embolization of cerebral aneurysms: a multicenter cohort study of 10 European neurovascular centers

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 Contour Neurovascular System for endovascular embolization of cerebral aneurysms: a multicenter cohort study of 10 European neurovascular centers

1. http://orcid.org/0000-0002-2952-3812Christoph J Griessenauer1,
2. http://orcid.org/0000-0001-5629-3023Sherief Ghozy2,
3. http://orcid.org/0000-0002-3185-0740Alessandra Biondi3,4,
4. http://orcid.org/0000-0003-0521-8570Constantin Hecker1,5,
5. http://orcid.org/0000-0003-1413-2699Fritz Wodarg6,
6. http://orcid.org/0000-0001-5640-7780Thomas Liebig7,
7. Tufail Patankar8,
8. Saleh Lamin9,
9. http://orcid.org/0000-0002-8024-4712Mario Martínez-Galdámez10,11,
10. http://orcid.org/0000-0003-4287-2627Christophe Cognard12,
11. http://orcid.org/0000-0001-8533-7478Jens Fiehler13,
12. Franziska Dorn14,
13. http://orcid.org/0000-0003-0131-5699Adam A Dmytriw15,16,
14. http://orcid.org/0000-0001-5572-7694Monika Killer-Oberpfalzer5,17

1. Correspondence to Dr Christoph J Griessenauer, Department of Neurosurgery, Christian Doppler Clinic, Paracelsus Medical University, Salzburg, Austria; christoph.griessenauer@gmail.com

Abstract

Background Intrasaccular devices have become increasingly popular in the treatment of cerebral aneurysms, particularly at the bifurcation. Here we evaluate the Contour Neurovascular System, an intrasaccular device for the endovascular treatment of cerebral aneurysms, in a multicenter cohort study, the largest to the best of our knowledge.

Methods Consecutive patients with intracranial aneurysms treated with the Contour Neurovascular System between February 2017 and October 2022 at 10 European neurovascular centers were prospectively collected and retrospectively reviewed. Patient and aneurysm characteristics, procedural details, and angiographic and clinical outcomes were evaluated.

Results During the study period, 279 aneurysms (median age of patients 60 years, IQR 52–68) were treated with Contour. In 83.2% of patients the device was placed electively, whereas the remaining patients were treated in the setting of acute subarachnoid hemorrhage. The most common locations were the middle cerebral artery (26.5%) followed by the anterior communicating region (26.2%). Median aneurysm dome and neck size were 5.2 mm (IQR 4.2–7) and 3.9 mm (IQR 3–5). Contour size 7 (39%) and 9 (25%) were most used. Thromboembolic and hemorrhagic complications occurred in 6.8% and 0.4% of aneurysms, respectively. Raymond-Roy 1 and 2 occlusions at last follow-up were achieved in 63.2% and 28.3%, respectively, resulting in adequate occlusion of 91.5% of aneurysms.

Conclusion This is the largest multicenter study reporting the outcome on the Contour Neurovascular System. At 1 year, the self-evaluated data on safety and efficacy are comparable to data of existing intrasaccular devices. Contour is a promising technology in the treatment of cerebral aneurysms.

Data availability statement

Data are available upon reasonable request. Data are available upon reasonable request and after execution of required necessary data use agreements.

https://doi.org/10.1136/jnis-2023-021378