Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,372 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke. DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Monday, May 27, 2024
Relationship between sleep, physical fitness, brain microstructure, and cognition in healthy older adults: A pilot study
Do you think you can get your stroke medical 'professionals' to get this testing done in stroke survivors? Because we need to know EXACTLY how to improve our cognition.
There is a critical need for biomarkers to monitor effects of modifiable lifestyle factors on brain health.
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This study assessed relationships between brain microstructure and sleep, physical fitness, and cognition in older adults.
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Neurite density was positively associated with executive functioning, language, processing speed, physical fitness and sleep.
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NDI was negatively associated with visuospatial functioning and ODI was negatively associated with physical fitness.
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NODDI is a potential biomarker for associations between brain microstructure and modifiable risk factors in aging.
Abstract
Background
There
is a critical need for neuroimaging markers of brain integrity to
monitor effects of modifiable lifestyle factors on brain health. This
observational, cross-sectional study assessed relationships between
brain microstructure and sleep, physical fitness, and cognition in
healthy older adults.
Methods
Twenty-three
adults aged 60 and older underwent whole-brain multi-shell diffusion
imaging, comprehensive cognitive testing, polysomnography, and exercise
testing. Neurite Orientation Dispersion and Density Imaging (NODDI) was
used to quantify neurite density (NDI) and orientation dispersion (ODI).
Diffusion tensor imaging (DTI) was used to quantify axial diffusivity
(AxD), fractional anisotropy (FA), mean diffusivity (MD), and radial
diffusivity (RD). Relationships between sleep efficiency (SE), time and
percent in N3 sleep, cognitive function, physical fitness (VO2 peak) and the diffusion metrics in regions of interest and the whole brain were evaluated.6microstructure and modifiable risk factors in
aging. If these associations are observable in clinical samples, NODDI
could be incorporated into clinical trials assessing the effects of
modifiable risk factors on brain integrity in aging and
neurodegenerative diseases.
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