Well, tPA is a failure most of the time anyway, only a 12% full success rate. So who the hell is finding something better?
Maybe these fourteen.
1. liposome-encapsulated hemoglobin written in Feb. 2010
2. bat saliva - Draculin written in May, 2011, up to 9 hours
3. cardiac glycosides written in Feb. 2006 - up to 6 hours
4.inhalation of nitric oxide written in March, 2012 - 48 hours to 7 days
5. Nitric oxide written in 2006, to be tested in humans yet.
6. xenon gas written in Feb. 2006, to be tested yet
7. caffeinol irish coffee injection written in April 2003 to be tested in humans
8. Docosahexaenoic acid (DHA), a component of fish oil written in Nov. 2010, up to 5 hours
9. nicotine written in July 2005, to be tested in humans
10. Viagra written in 2002, to be tested in humans, for 7 days
11. PSD-95 inhibitors written in 2012, tested in monkeys 3 hours
11. Enzogenol written in Nov. 2011 for New Zealand
12 edaravone approved in Japan since 2001
13. nitroglycerin instructions
14. benzodiazepine inverse agonist written in Nov. 2010
Don't they have any understanding that even if the clot is blown out via tPA or picked out that the neuronal cascade of death still occurs?
Is everyone stupid?
http://www.medpagetoday.com/MeetingCoverage/WCN/41792
Treating ischemic stroke patients with endovascular therapy when
initial tPA thrombolysis was unsuccessful led to good 3-month outcomes
in most cases, a researcher said here.
Among 23 stroke patients in
a prospective multicenter study, 15 were rated with modified Rankin
scores of 2 or less when evaluated 3 months after failed thrombolysis
followed by mechanical thrombectomy, according to Philippe Desfontaines, MD, of CHC St.-Joseph in Liege, Belgium.
More at link.
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