Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, March 3, 2011

xenon gas and stroke rehab

I know this was not directly tested in stroke rehab but it sounds like something fascinating to followup on.

xenon gas and stroke rehab


Scientists have successfully conducted the first clinical trial giving xenon gas to patients undergoing coronary artery bypass grafting in order to safeguard against postoperative brain damage that can occur following this procedure.
Research published in Anesthesiology shows how the team safely gave xenon to 12 patients undergoing coronary artery bypass grafting while on cardiopulmonary artery bypass, a step which could eventually lead to new treatments for people suffering from illnesses that damage nerve cells, such as strokes, and brain and spinal cord injuries.
Earlier preclinical work by the team showed that xenon was effective as a neuroprotectant, stopping processes present during strokes or brain and spinal cord injuries that would damage nerve cells. They found that xenon was capable of blocking the effects of a particular type of glutamate receptor, the same receptor implicated in the pathway that leads to nerve cell death.

The discovery that xenon acted as a neuroprotectant came about when Professor Nick Franks Opens in new window, a biophysicist from Imperial College London was investigating possible molecular targets which could be responsible for the action of different anaesthetics.
Professor Mervyn Maze Opens in new window, an anaesthetist from Imperial College London who has collaborated with Professor Franks in the xenon research programme, said: "We knew from our earlier studies that xenon was effective in stopping damaged nerve cells from dying, but this study is of tremendous importance as it shows that it is feasible to administer xenon safely to a population of patients at risk for developing brain damage. What we need now is a clinical trial to test the efficacy of xenon in large numbers of patients.
"Xenon could provide a whole new way of treating nerve damaging illnesses. Although we can stop people dying from these illnesses, there is not much we can do to stop the nerve damage that ultimately leads to devastating long-term disability."
Professor Franks added: "We hope xenon could be developed as a novel treatment. It is naturally occurring, and more importantly, its known lack of toxicity makes it an attractive candidate as a neuroprotectant in humans.
"Ultimately, we hope xenon could become part of standard medical treatment, with paramedics being able to administer it to stroke and brain-injured victims to stop ongoing nerve cell death."

And this makes me wonder if my earlier post on bubbles and ultrasound had come to an incorrect conclusion that the vibrating bubbles were the reason for the benefit rather than the xenon gas they used in the bubbles.
http://oc1dean.blogspot.com/2011/03/bubbles-with-ultrasound-stroke-drugs.html
Something for researchers to followup on.
I wonder if xenon gas causes the same voice response as helium?

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