Deans' stroke musings: The Role of Vitamins in Neurodegeneration: A Brief Review of Mechanisms, Clinical Evidence, and Therapeutic Perspectives

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, July 17, 2025

The Role of Vitamins in Neurodegeneration: A Brief Review of Mechanisms, Clinical Evidence, and Therapeutic Perspectives

Pretty useless, nothing on how to test for this and NOTHING ON AMOUNTS!

The Role of Vitamins in Neurodegeneration: A Brief Review of Mechanisms, Clinical Evidence, and Therapeutic Perspectives

Alberto Raggi 1, Raffaele Ferri 2

Affiliations

PMID: 40659185
DOI: 10.1111/psyg.70071

Abstract

This review evaluates the role of vitamins in neurodegeneration.

Low levels of B vitamins have been associated with cognitive decline. B vitamins may help inhibit amyloid plaque aggregation.

Vitamin D deficiency has been linked to an increased risk of cognitive impairment, correlating with Alzheimer's pathology.

Vitamin E may help delay Alzheimer's disease progression and support functional abilities.

In Parkinson's disease, vitamin D shows promise in reducing dopaminergic neuron loss and improving motor and cognitive outcomes.

Vitamin C reduces oxidative stress and preserves neuronal integrity.

Vitamin K has gained attention for its role in cognitive health, with studies suggesting that higher levels may be linked to improved cognitive performance.(Not to be taken while on warfarin(rat poison)) In conclusion, a better understanding of the translational potential of these vitamins may inform preventive and therapeutic strategies for neurodegenerative diseases. Clinicians should consider vitamin supplementation for aging-related conditions. Further studies are needed to confirm its therapeutic potential and clarify underlying mechanisms in neurodegeneration.

Keywords: Alzheimer's disease; cognitive impairment; neurodegeneration; neuroprotection; oxidative damage; vitamin supplementation.

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