Colchicine prevents rise in total plaque volume for patients with stable CAD

 I bet we don't have enough brains in stroke to say; 'Maybe this would help in stroke also!'

colchicine (23 posts to December 2011)

I bet your incompetent doctor and hospital DID NOTHING WITH THIS EARLIER RESEARCH! That's why they are incompetent! DOING NOTHING!

Colchicine prevents rise in total plaque volume for patients with stable CAD

Key takeaways:

• For patients with stable coronary artery disease, colchicine conferred lower total plaque volume as measured by coronary CT angiography vs. placebo.
• There was no effect on volume of low attenuation plaque.

CHICAGO — Among patients with stable coronary artery disease, colchicine lowered total plaque volume compared with placebo but had no impact on low attenuation plaque volume, researchers reported.

“If we can show both outcome data and mechanistic plaque data that are concordant, we should ... get more comfortable with these interventions, and I think colchicine is going to be one that will be used more in clinical practice based on the available clinical data,” Matthew J. Budoff, MD, investigator at The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, professor of medicine at the David Geffen School of Medicine at UCLA and program director and director of cardiac CT, division of cardiology, at Harbor-UCLA Medical Center, told Healio.

Data were derived from Budoff MJ, et al. Featured clinical research IV. Presented at: American College of Cardiology Scientific Session; March 29-31, 2025; Chicago (hybrid meeting).