Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, April 7, 2025

Daily Heart Rate Per Step (DHRPS): A Wearables Metric Associated with Cardiovascular Disease in a Cross-Sectional Study of the All of Us Research Program

Your Heart’s New Metric? What You Need to Know About DHRPS

A new stat is making waves in the wearable health world: Daily Heart Rate Per Step (DHRPS). It sounds high-tech—and it is. But is it worth tracking?

According to new research published in the Journal of the American Heart Association, a higher DHRPS (your average heart rate divided by total daily steps) may predict a greater risk of chronic conditions like hypertension, elevated blood sugar, and metabolic syndrome.

But Super Age advisor Dr. Michael Roizen, Chief Wellness Officer of the Cleveland Clinic, urges perspective. DHRPS is what he calls "a computed process variable"—a helpful clue, not a final answer.

👉 Here's why he's not ready to use it as a tracking variable and what to track instead.

No idea what mine is, no daily heart rate monitor.

 Daily Heart Rate Per Step (DHRPS): A Wearables Metric Associated with
Cardiovascular Disease in a Cross-Sectional Study of the All of Us Research
Program

Zhanlin Chen, MS1; Charles T. Wang, BA1; Carolyn J. Hu, BS1; Kendra Ward, MD,
MSCI2; Abel Kho, MD3; Gregory Webster, MD, MPH2

1. Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

2. Division of Cardiology, Department of Pediatrics, Ann & Robert H. Lurie Children's
Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago,
IL, 60611, USA.

3. Center for Health Information Partnerships, Northwestern University Feinberg School
of Medicine, Chicago, IL, USA

Correspondence: Gregory Webster, MD, MPH, Division of Cardiology, Department of
Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University
Feinberg School of Medicine, 225 E Chicago Avenue, Chicago, IL 60611, Telephone: (312) 227-
4397, Email:
rgwebster@luriechildrens.org
Subject Terms: Biomarkers; Risk Factors; Digital Health
Accepted ArticleAccepted Article

Abstract

Background: 

Simple biometrics such as peak heart rate and exercise duration remain core
predictors of cardiovascular disease (CVD). Commercial wearable devices track physical and
cardiac electrical activity. Detailed, longitudinal data collection from wearables presents a valuable opportunity to identify new factors associated with CVD.


Methods: 

This cross-sectional study analyzed 6,947 participants in the Fitbit Bring-Your-Own-
Device Project, a subset of the All of Us Research Program. The primary exposure Daily Heart
Rate Per Step (DHRPS) was defined as the average daily heart rate divided by steps per day. Our analysis correlated DHRPS with established CVD factors (type 2 diabetes, hypertension, stroke, heart failure, coronary atherosclerosis, myocardial infarction) as primary outcomes. We also performed a DHRPS-based phenome-wide association study (PheWAS) on the spectrum of human disease traits for all 1,789 disease codes across 17 disease categories. Secondary outcomes included maximum metabolic equivalents (METs) achieved on cardiovascular treadmill exercise stress testing.


Results: 

We examined 5.8 million person-days and 51 billion total steps of individual-level Fitbit data paired with electronic health record data. Elevated DHRPS was associated with type 2diabetes (OR 2.03 [95% CI 1.70-2.42]), hypertension (OR 1.63 [95% CI 1.32-2.02]), heart failure(OR 1.77 [95% CI 1.00-3.14]), and coronary atherosclerosis (OR 1.44 [95% CI 1.14-1.82]), even after adjusting for daily heart rate and step count. DHRPS also had stronger correlations with max METs achieved on exercise stress testing compared to steps per day (∆ρ=0.04, p<0.001) and heart rate (∆ρ=0.31, p<0.001). Lastly, DHRPS-based PheWAS demonstrated stronger associations with
CVD factors (p<1×10-55) compared to daily heart rate or step count.

Conclusions: 

In the All of Us Research Program Fitbit Bring-Your-Own-Device Project, DHRPS was an easy-to-calculate wearables metric and was more strongly associated with cardiovascular fitness and CVD outcomes than daily heart rate and step count.

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