http://stroke.ahajournals.org/content/47/Suppl_1/ATP340.short
+ Author Affiliations
Abstract
Background and aims:
Recently, safety concerns were raised about the radiation dose for acute
ischemic stroke (AIS) patients undergoing computed
tomography (CT), CT angiography (CTA) and CT
perfusion (CTP). We evaluated precise radiation dose to the brain during
various
imaging studies in our AIS patients.
Methods: Brain imaging
was performed with 64-detector row CT scanner (Phillips-iCT256) using
standard protocols recommended by American
Association of Physicist in Medicine. For each
procedure, volume weighted CT dose index (CTDIvol, mGy) and dose-length
product
DLP (mGy.cm) were obtained from dose reports
generated at the time of acquisition. Organ specific dose to brain, eye,
bone
marrow and thyroid were also obtained. The
estimates of cancer risk were interpolated.
Results: In this
prospective study, a total of 18 patients who underwent CT, CTA as well
as CTP were included. Mean DLP for non-enhanced
CT, CTA and CTP were 1068.25, 1150 and 1197
mGy.cm, respectively. Corresponding whole body effective dose for the
CT, CTA
and CTP were calculated as 2.57, 2.6, 2.4 mSv,
respectively. Cumulative doses to the brain, eyes, bone marrow and
thyroid
gland were 33.81, 32.8, 1.21 and 1.31 mGy for
the non-contrast brain CT. CTDIvol measurements for different protocols
tested
by the phantom were in agreement with values
given in dose reports.
Conclusions: The
effective radiation doses are less than previously reported and much
below the radiation threshold level for deterministic
effects for brain and optic lens (500-2000mGy).
Estimated life-time attributable cancer risks are very low with the
current
radiation doses.
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