http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=10255541&utm_source=Issue_Alert&utm_medium=RSS&utm_campaign=PHN
Maria Dimitrioua1 c1, Loukianos S Rallidisa2, Eirini V Theodorakia1, Ioanna Panagiota Kalafatia1, Genovefa Kolovoua3 and George V Dedoussisa1 c1
a1 Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, El. Venizelou 70, 17671 Athens, Greecea2 Second Department of Cardiology, Attikon Hospital, School of Medicine, University of Athens, Athens, Greece
a3 First Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece
Abstract
Objective
The aims of the current report are to present the demographic
characteristics, clinical characteristics/biochemical indices and
lifestyle habits of the population and to explore the potential
association of exclusive olive oil consumption, in relation to lifestyle
factors, with coronary artery disease risk.Design Demographic, lifestyle, dietary and biochemical variables were recorded. Logistic regression analysis was performed in order to estimate the relative risks of developing coronary artery disease.
Setting The Hellenic study of Interactions between Single nucleotide polymorphisms and Eating in Atherosclerosis Susceptibility (THISEAS), a medical centre-based case–control study conducted in Greek adults.
Subjects We consecutively enrolled 1221 adult patients with coronary artery disease and 1344 adult controls.
Results A higher prevalence of the conventional established risk factors was observed in cases than in controls. Physical activity level was higher in controls (1·4 (sd 0·2) than in cases (1·3 (sd 0·3); P<0·001). Regarding current and ex-smokers, the case group reported almost double the pack-years of the control group (54·6 (sd 42·8) v. 28·3 (sd 26·3), respectively; P<0·001). Exclusive olive oil consumption was associated with 37 % lower likelihood of developing coronary artery disease, even after taking into account adherence to the Mediterranean diet (OR=0·63; 95 % CI 0·42, 0·93; P=0·02).
Conclusions Exclusive olive oil consumption was associated with lower risk of coronary artery disease, even after adjusting for adoption of an overall healthy dietary pattern such as the Mediterranean diet.
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